Induction of autophagy via the TLR4/NF-&#954;B signaling pathway by astragaloside â£ contributes to the amelioration of inflammation in RAW264.7 cells.

Ying, Yi; Sun, Chun-Bin; Zhang, Si-Qi; Chen, Bo-Jun; Yu, Jing-Ze; Liu, Fei-Yu; Wen, Jing; Hou, Jiong; Han, Si-Si; Yan, Jin-Yuan; Yang, Zhong-Shan; Xiong, Lei

Induction of autophagy via the TLR4/NF-κB signaling pathway by astragaloside â£ contributes to the amelioration of inflammation in RAW264.7 cells.

Ying, Yi; Sun, Chun-Bin; Zhang, Si-Qi; Chen, Bo-Jun; Yu, Jing-Ze; Liu, Fei-Yu; Wen, Jing; Hou, Jiong; Han, Si-Si; Yan, Jin-Yuan; Yang, Zhong-Shan; Xiong, Lei.

Afiliação

Ying Y; Yunnan Provincial Key Laboratory of Molecular Biology for Sinomedicine, Yunnan University of Chinese Medicine, Kunming, Yunnan, China.
Sun CB; Yunnan Provincial Key Laboratory of Molecular Biology for Sinomedicine, Yunnan University of Chinese Medicine, Kunming, Yunnan, China.
Zhang SQ; Yunnan Provincial Key Laboratory of Molecular Biology for Sinomedicine, Yunnan University of Chinese Medicine, Kunming, Yunnan, China.
Chen BJ; Yunnan Provincial Key Laboratory of Molecular Biology for Sinomedicine, Yunnan University of Chinese Medicine, Kunming, Yunnan, China; The First Clinical Medicine College, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Yu JZ; The Key Laboratory of Molecular Epigenetics of MOE, Institute of Genetics and Cytology, Northeast Normal University, Changchun, Jilin, China.
Liu FY; Yunnan Provincial Key Laboratory of Molecular Biology for Sinomedicine, Yunnan University of Chinese Medicine, Kunming, Yunnan, China.
Wen J; Yunnan Provincial Key Laboratory of Molecular Biology for Sinomedicine, Yunnan University of Chinese Medicine, Kunming, Yunnan, China.
Hou J; Yunnan Provincial Key Laboratory of Molecular Biology for Sinomedicine, Yunnan University of Chinese Medicine, Kunming, Yunnan, China.
Han SS; PingHu Hospital Shenzhen University, Shenzhen University, Shenzhen, Guangdong, China.
Yan JY; Central Laboratory, Kunming Medical University Second Hospital, Kunming, Yunnan, China. Electronic address: 399109308@qq.com.
Yang ZS; Yunnan Provincial Key Laboratory of Molecular Biology for Sinomedicine, Yunnan University of Chinese Medicine, Kunming, Yunnan, China; Key Laboratory of Microcosmic Syndrome Differentiation, Education Department of Yunnan, Kunming, Yunnan University of Chinese Medicine, Yunnan, China. Electronic add
Xiong L; Yunnan Provincial Key Laboratory of Molecular Biology for Sinomedicine, Yunnan University of Chinese Medicine, Kunming, Yunnan, China; The First Clinical Medicine College, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China. Electronic address: ynzyydxxl@sina.com.

Biomed Pharmacother ; 137: 111271, 2021 May.

Article em En | MEDLINE | ID: mdl-33561643

Assuntos

Anti-Inflamatórios/farmacologia; Autofagia/efeitos dos fármacos; Inflamação/prevenção & controle; Macrófagos/efeitos dos fármacos; NF-kappa B/metabolismo; Saponinas/farmacologia; Receptor 4 Toll-Like/metabolismo; Triterpenos/farmacologia; Animais; Citocinas/metabolismo; Inflamação/imunologia; Inflamação/metabolismo; Inflamação/patologia; Macrófagos/imunologia; Macrófagos/metabolismo; Macrófagos/ultraestrutura; Camundongos; Fosforilação; Células RAW 264.7; Transdução de Sinais

Palavras-chave

Astragaloside â£; Autophagy; Inflammation; TLR4/NF-κB signaling pathway

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saponinas / Autofagia / Triterpenos / NF-kappa B / Receptor 4 Toll-Like / Inflamação / Macrófagos / Anti-Inflamatórios Limite: Animals Idioma: En Revista: Biomed Pharmacother Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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