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Propranolol Reduces the Development of Lesions and Rescues Barrier Function in Cerebral Cavernous Malformations: A Preclinical Study.
Oldenburg, Joppe; Malinverno, Matteo; Globisch, Maria Ascencion; Maderna, Claudio; Corada, Monica; Orsenigo, Fabrizio; Conze, Lei Liu; Rorsman, Charlotte; Sundell, Veronica; Arce, Maximiliano; Smith, Ross O; Yau, Anthony C Y; Billström, Gry Hulsart; Mägi, Caroline Öhman; Beznoussenko, Galina V; Mironov, Alexander A; Fernando, Dinesh; Daniel, Geoffrey; Olivari, Davide; Fumagalli, Francesca; Lampugnani, Maria Grazia; Dejana, Elisabetta; Magnusson, Peetra U.
Afiliação
  • Oldenburg J; Department of Immunology, Genetics and Pathology (J.O., M.A.G., L.L.C., C.R., V.S., M.A., R.O.S., A.C.Y.Y., E.D., P.U.M.), Uppsala University, Sweden.
  • Malinverno M; Vascular Biology Unit (M.M., C.M., M.C., F.O., G.V.B., M.G.L., E.D.), The FIRC Institute of Molecular Oncology Foundation, Milan, Italy.
  • Globisch MA; Department of Immunology, Genetics and Pathology (J.O., M.A.G., L.L.C., C.R., V.S., M.A., R.O.S., A.C.Y.Y., E.D., P.U.M.), Uppsala University, Sweden.
  • Maderna C; Vascular Biology Unit (M.M., C.M., M.C., F.O., G.V.B., M.G.L., E.D.), The FIRC Institute of Molecular Oncology Foundation, Milan, Italy.
  • Corada M; Vascular Biology Unit (M.M., C.M., M.C., F.O., G.V.B., M.G.L., E.D.), The FIRC Institute of Molecular Oncology Foundation, Milan, Italy.
  • Orsenigo F; Vascular Biology Unit (M.M., C.M., M.C., F.O., G.V.B., M.G.L., E.D.), The FIRC Institute of Molecular Oncology Foundation, Milan, Italy.
  • Conze LL; Department of Immunology, Genetics and Pathology (J.O., M.A.G., L.L.C., C.R., V.S., M.A., R.O.S., A.C.Y.Y., E.D., P.U.M.), Uppsala University, Sweden.
  • Rorsman C; Department of Immunology, Genetics and Pathology (J.O., M.A.G., L.L.C., C.R., V.S., M.A., R.O.S., A.C.Y.Y., E.D., P.U.M.), Uppsala University, Sweden.
  • Sundell V; Department of Immunology, Genetics and Pathology (J.O., M.A.G., L.L.C., C.R., V.S., M.A., R.O.S., A.C.Y.Y., E.D., P.U.M.), Uppsala University, Sweden.
  • Arce M; Department of Immunology, Genetics and Pathology (J.O., M.A.G., L.L.C., C.R., V.S., M.A., R.O.S., A.C.Y.Y., E.D., P.U.M.), Uppsala University, Sweden.
  • Smith RO; Department of Immunology, Genetics and Pathology (J.O., M.A.G., L.L.C., C.R., V.S., M.A., R.O.S., A.C.Y.Y., E.D., P.U.M.), Uppsala University, Sweden.
  • Yau ACY; Department of Immunology, Genetics and Pathology (J.O., M.A.G., L.L.C., C.R., V.S., M.A., R.O.S., A.C.Y.Y., E.D., P.U.M.), Uppsala University, Sweden.
  • Billström GH; Department of Surgical Sciences, Orthopaedics (G.H.B.), Uppsala University, Sweden.
  • Mägi CÖ; Department of Materials and Science and Engineering, Applied Materials Science (C.O.M.), Uppsala University, Sweden.
  • Beznoussenko GV; Vascular Biology Unit (M.M., C.M., M.C., F.O., G.V.B., M.G.L., E.D.), The FIRC Institute of Molecular Oncology Foundation, Milan, Italy.
  • Mironov AA; Electron Microscopic Laboratory (G.V.B., A.A.M.), The FIRC Institute of Molecular Oncology Foundation, Milan, Italy.
  • Fernando D; Electron Microscopic Laboratory (G.V.B., A.A.M.), The FIRC Institute of Molecular Oncology Foundation, Milan, Italy.
  • Daniel G; Department of Biomaterials and Technology/Wood Science, Swedish University of Agricultural Sciences, Uppsala (D.F., G.D.).
  • Olivari D; Department of Biomaterials and Technology/Wood Science, Swedish University of Agricultural Sciences, Uppsala (D.F., G.D.).
  • Fumagalli F; Cardiopulmonary Physiopathology Laboratory, Cardiovascular Medicine Department, Instituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy (D.O., F.F.).
  • Lampugnani MG; Cardiopulmonary Physiopathology Laboratory, Cardiovascular Medicine Department, Instituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy (D.O., F.F.).
  • Dejana E; Vascular Biology Unit (M.M., C.M., M.C., F.O., G.V.B., M.G.L., E.D.), The FIRC Institute of Molecular Oncology Foundation, Milan, Italy.
  • Magnusson PU; Mario Negri Institute for Pharmacological Research, Milan, Italy (M.G.L.).
Stroke ; 52(4): 1418-1427, 2021 04.
Article em En | MEDLINE | ID: mdl-33618555
[Figure: see text].
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Propranolol / Neoplasias do Sistema Nervoso Central / Hemangioma Cavernoso do Sistema Nervoso Central Limite: Animals Idioma: En Revista: Stroke Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Suécia
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Propranolol / Neoplasias do Sistema Nervoso Central / Hemangioma Cavernoso do Sistema Nervoso Central Limite: Animals Idioma: En Revista: Stroke Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Suécia