The SimpliciT1 Study: A Randomized, Double-Blind, Placebo-Controlled Phase 1b/2 Adaptive Study of TTP399, a Hepatoselective Glucokinase Activator, for Adjunctive Treatment of Type 1 Diabetes.

Klein, Klara R; Freeman, Jennifer L R; Dunn, Imogene; Dvergsten, Chris; Kirkman, M Sue; Buse, John B; Valcarce, Carmen

Klein, Klara R; Freeman, Jennifer L R; Dunn, Imogene; Dvergsten, Chris; Kirkman, M Sue; Buse, John B; Valcarce, Carmen.

Afiliação

Klein KR; Division of Endocrinology and Metabolism, University of North Carolina School of Medicine, Chapel Hill, NC klara_klein@med.unc.edu.
Freeman JLR; vTv Therapeutics LLC, High Point, NC.
Dunn I; vTv Therapeutics LLC, High Point, NC.
Dvergsten C; vTv Therapeutics LLC, High Point, NC.
Kirkman MS; Division of Endocrinology and Metabolism, University of North Carolina School of Medicine, Chapel Hill, NC.
Buse JB; Division of Endocrinology and Metabolism, University of North Carolina School of Medicine, Chapel Hill, NC.

Diabetes Care ; 44(4): 960-968, 2021 04.

Article em En | MEDLINE | ID: mdl-33622669

Assuntos

Diabetes Mellitus Tipo 1; Glucoquinase; Diabetes Mellitus Tipo 1/tratamento farmacológico; Método Duplo-Cego; Hemoglobinas Glicadas/análise; Humanos; Hipoglicemiantes/efeitos adversos; Insulina; Compostos Orgânicos; Resultado do Tratamento

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 1 / Glucoquinase Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Revista: Diabetes Care Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Nova Caledônia

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