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A 3-armed multicenter randomized controlled trial: Placental Transfusion in Very Preterm Infants (PT-VPI).
Yue, Guang; Wu, Yan; Zhao, Fangping; Zhang, Chunyi; Zhao, Dan; Lu, Jingjie; Fang, Qiaoyan; Li, Xia; Wei, Yijun; Qian, Miao; Yi, Lin; Zheng, Shan; Ba, Ruihua; Luo, Liqian; Luo, Jiping; Zhao, Shuai; Lu, Jiangyi; Huang, Xia; Wei, Guoqing; Xi, Yufeng; Gao, Shuqiang; Hu, Xuhong; Ju, Rong.
Afiliação
  • Yue G; Neonatal Department, Chengdu Women's and Children's Central Hospital, School of Medicine, School of Medicine, University of Electronic Science and Technology of China, Chengdu, PR China.
  • Wu Y; Neonatal Department, Chongqing Health Center for Women and Children, Chongqing, PR China.
  • Zhao F; Neonatal Department, Gansu Provincial Maternity and Child-Care Hospital, Lanzhou, PR China.
  • Zhang C; Neonatal Department, Guangdong Women and Children Hospital, Guangzhou, PR China.
  • Zhao D; Neonatal Department, Maternity and Child-Care Hospital of Guangxi Zhuang Autonomous Region, Nanning, PR China.
  • Lu J; Neonatal Department, Guiyang Maternal and Child Health Hospital, Guizhou, PR China.
  • Fang Q; Neonatal Department, Hunan Provincial Maternal and Child Healthcare Hospital, Changsha, PR China.
  • Li X; Neonatal Department, Jinan Maternity and Child-Care Hospital, Jinan, PR China.
  • Wei Y; Neonatal Department, Liuzhou Maternity and Child Healthcare Hospital, Liuzhou, PR China.
  • Qian M; Neonatal Department, Nanjing Maternity and Child Health Care Hospital, Nanjing, PR China.
  • Yi L; Neonatal Department, Affiliated Shenzhen Maternity & Child Healthcare Hospital, Southern Medical University, Shenzhen, PR China.
  • Zheng S; Neonatal Department, Tianjin Central Hospital of Obstetrics and Gynecology, Tianjin, PR China.
  • Ba R; Neonatal Department, Women and Children's Hospital, School of Medicine, Xiamen University, Xiamen, PR China.
  • Luo L; Neonatal Department, Northwest Women's and Children's Hospital, Xi'an, PR China.
  • Luo J; Neonatal Department, Xichang People's Hospital, Xichang, PR China.
  • Zhao S; Neonatal Department, The Affiliated Hospital of Southwest Medical University, Luzhou, PR China.
  • Lu J; Neonatal Department, Chengdu Women's and Children's Central Hospital, School of Medicine, School of Medicine, University of Electronic Science and Technology of China, Chengdu, PR China.
  • Huang X; Neonatal Department, Chengdu Women's and Children's Central Hospital, School of Medicine, School of Medicine, University of Electronic Science and Technology of China, Chengdu, PR China.
  • Wei G; Neonatal Department, Chengdu Women's and Children's Central Hospital, School of Medicine, School of Medicine, University of Electronic Science and Technology of China, Chengdu, PR China.
  • Xi Y; Neonatal Department, Chengdu Women's and Children's Central Hospital, School of Medicine, School of Medicine, University of Electronic Science and Technology of China, Chengdu, PR China.
  • Gao S; Neonatal Department, Chengdu Women's and Children's Central Hospital, School of Medicine, School of Medicine, University of Electronic Science and Technology of China, Chengdu, PR China.
  • Hu X; Neonatal Department, Chengdu Women's and Children's Central Hospital, School of Medicine, School of Medicine, University of Electronic Science and Technology of China, Chengdu, PR China.
  • Ju R; Neonatal Department, Chengdu Women's and Children's Central Hospital, School of Medicine, School of Medicine, University of Electronic Science and Technology of China, Chengdu, PR China. Electronic address: jurong@uestc.edu.cn.
Contemp Clin Trials ; 103: 106337, 2021 04.
Article em En | MEDLINE | ID: mdl-33662589
ABSTRACT
Preterm infants constitute an important proportion of neonatal deaths and various complications, and very preterm infants (VPI) are more likely to develop severe complications, such as intraventricular hemorrhage (IVH), anemia, and sepsis. It has been confirmed that placental transfusion can supplement blood volume in infants and reduce preterm-associated complications, which is further conducive to the development of the nervous system and a better long-term prognosis. Based on these advantages, placental transfusion has been widely used in VPI. There are three main types of placental transfusion delayed cord clamping (DCC), intact umbilical cord milking (I-UCM), and cut umbilical cord milking (C-UCM). However, the optimal method for PT-VPI remains controversial, and it is urgent to identify the best method of placental transfusion. We plan to fully evaluate the safety and effectiveness of these three placental transfusion methods in VPI in a 3-arm multicenter randomized controlled trial Placental Transfusion in Very Preterm Infants (PT-VPI). Trial registration chictr.org.cn, number ChiCTR2000030953.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Placenta / Recém-Nascido Prematuro Tipo de estudo: Clinical_trials Limite: Female / Humans / Newborn / Pregnancy Idioma: En Revista: Contemp Clin Trials Assunto da revista: MEDICINA / TERAPEUTICA Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Placenta / Recém-Nascido Prematuro Tipo de estudo: Clinical_trials Limite: Female / Humans / Newborn / Pregnancy Idioma: En Revista: Contemp Clin Trials Assunto da revista: MEDICINA / TERAPEUTICA Ano de publicação: 2021 Tipo de documento: Article