Selective mediation of ovarian cancer SKOV3 cells death by pristine carbon quantum dots/Cu<sub>2</sub>O composite through targeting matrix metalloproteinases, angiogenic cytokines and cytoskeleton.

Chen, Daomei; Li, Bin; Lei, Tao; Na, Di; Nie, Minfang; Yang, Yepeng; He, Zijuan; Wang, Jiaqiang

Selective mediation of ovarian cancer SKOV3 cells death by pristine carbon quantum dots/Cu₂O composite through targeting matrix metalloproteinases, angiogenic cytokines and cytoskeleton.

Chen, Daomei; Li, Bin; Lei, Tao; Na, Di; Nie, Minfang; Yang, Yepeng; He, Zijuan; Wang, Jiaqiang.

Afiliação

Chen D; National Center for International Research On Photoelectric and Energy Materials, School of Materials and Energy, Yunnan University, Kunming, 650091, People's Republic of China.
Li B; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan University, Kunming, 650091, People's Republic of China.
Lei T; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan University, Kunming, 650091, People's Republic of China. libin36@ynu.edu.cn.
Na D; National Center for International Research On Photoelectric and Energy Materials, School of Materials and Energy, Yunnan University, Kunming, 650091, People's Republic of China.
Nie M; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan University, Kunming, 650091, People's Republic of China.
Yang Y; School of Chemical Sciences & Technology, Yunnan University, Kunming, 650091, People's Republic of China.
Congjia; National Center for International Research On Photoelectric and Energy Materials, School of Materials and Energy, Yunnan University, Kunming, 650091, People's Republic of China.
Xie; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan University, Kunming, 650091, People's Republic of China.
He Z; School of Chemical Sciences & Technology, Yunnan University, Kunming, 650091, People's Republic of China.
Wang J; National Center for International Research On Photoelectric and Energy Materials, School of Materials and Energy, Yunnan University, Kunming, 650091, People's Republic of China.

J Nanobiotechnology ; 19(1): 68, 2021 Mar 04.

Article em En | MEDLINE | ID: mdl-33663548

Assuntos

Carbono/farmacologia; Morte Celular/efeitos dos fármacos; Citocinas/metabolismo; Citoesqueleto/metabolismo; Metaloproteinases da Matriz/metabolismo; Nanocompostos/química; Neoplasias Ovarianas/tratamento farmacológico; Pontos Quânticos/química; Indutores da Angiogênese; Inibidores da Angiogênese/química; Inibidores da Angiogênese/farmacologia; Animais; Antineoplásicos/química; Antineoplásicos/farmacologia; Apoptose/efeitos dos fármacos; Ciclo Celular; Pontos de Checagem do Ciclo Celular/efeitos dos fármacos; Linhagem Celular Tumoral; Cobre/química; Cobre/farmacologia; Regulação para Baixo/efeitos dos fármacos; Feminino; Humanos; Metaloproteinase 9 da Matriz/metabolismo; Camundongos; Receptor 2 de Fatores de Crescimento do Endotélio Vascular/metabolismo

Palavras-chave

Angiogenesis; Cellular microenvironment; Cytoskeleton; F-actin; MMP-2/9; Matrix metalloproteinases; Ovarian cancer SKOV3 cells; VEGFR2

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Citoesqueleto / Carbono / Citocinas / Morte Celular / Metaloproteinases da Matriz / Pontos Quânticos / Nanocompostos Limite: Animals / Female / Humans Idioma: En Revista: J Nanobiotechnology Ano de publicação: 2021 Tipo de documento: Article

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