Tissue tolerance to cyanoacrylate adhesives for closure of surgical wounds in Trachemys scripta skin.
Vet Rec
; 188(5): e59, 2021 03.
Article
em En
| MEDLINE
| ID: mdl-33666962
ABSTRACT
BACKGROUND:
The aim of this study was to evaluate the histological tolerance of medical cyanoacrylate adhesives (CAs), butyl-CA and octyl-CA, applied by two different methods in surgical skin incisions of T. scripta.METHODS:
A two-trial controlled blind study each one including 12 female adult T. scripta turtles. Two 1-cm long full-thickness surgical skin incisions were made on the dorsal aspect of each hind limb. In trial 1 CAs were applied superficially over the apposed wound edges; each animal's four wounds were closed using butyl-CA, octyl-CA and ethyl-CA or absorbable suture as controls. In trial 2 adhesives were applied holding wound edges everted, and octyl-CA was replaced by a non-sutured control wound. At each time point (2, 7, 14 and 21 days) all wounds from three randomly chosen animals were biopsied.RESULTS:
Medical grade CAs did not induce any sign of tissue damage and/or inflammatory reaction attributable to histotoxicity independently of the method of application. Wound dehiscence rate was higher when CAs were applied superficially over the apposed wound edges.CONCLUSIONS:
Octyl and butyl-CA are well tolerated by turtles' soft skin but because of their high rate of dehiscence they are not recommended in high tension wounds; use in low tension wounds needs further investigation.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Adesivos Teciduais
/
Tartarugas
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Cianoacrilatos
/
Ferida Cirúrgica
Limite:
Animals
Idioma:
En
Revista:
Vet Rec
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Espanha