Aldosterone alleviates lipopolysaccharide-induced acute lung injury by regulating epithelial sodium channel through PI3K/Akt/SGK1 signaling pathway.

Fei, Xiu; Ziqian, Yu; Bingwu, Yang; Min, Li; Xinmiao, Xian; Zhen, Meng; Lirong, Guo; Song, Wang

Fei, Xiu; Ziqian, Yu; Bingwu, Yang; Min, Li; Xinmiao, Xian; Zhen, Meng; Lirong, Guo; Song, Wang.

Afiliação

Fei X; Department of Blood Transfusion, Liaocheng People's Hospital, #67 Dongchangxi Road, Liaocheng, 252000, China.
Ziqian Y; Department of Clinical Laboratory, Liaocheng Veterans Hospital, #2 Gaodong Street, Liaocheng, 252000, China.
Bingwu Y; Procesion Biomedical Lab, Liaocheng People's Hospital, Medical College of Liaocheng University, #67 Dongchangxi Road, Liaocheng, 252000, China.
Min L; Procesion Biomedical Lab, Liaocheng People's Hospital, Medical College of Liaocheng University, #67 Dongchangxi Road, Liaocheng, 252000, China.
Xinmiao X; Procesion Biomedical Lab, Liaocheng People's Hospital, Medical College of Liaocheng University, #67 Dongchangxi Road, Liaocheng, 252000, China.
Zhen M; Procesion Biomedical Lab, Liaocheng People's Hospital, Medical College of Liaocheng University, #67 Dongchangxi Road, Liaocheng, 252000, China.
Lirong G; Nursing School of Jilin University, Changchun, Jilin, 130021, China. Electronic address: guolr@jlu.edu.cn.
Song W; Procesion Biomedical Lab, Liaocheng People's Hospital, Medical College of Liaocheng University, #67 Dongchangxi Road, Liaocheng, 252000, China. Electronic address: wslcrmyy@sina.com.

Mol Cell Probes ; 57: 101709, 2021 06.

Article em En | MEDLINE | ID: mdl-33713776

Assuntos

Lesão Pulmonar Aguda; Canais Epiteliais de Sódio; Lesão Pulmonar Aguda/induzido quimicamente; Lesão Pulmonar Aguda/tratamento farmacológico; Aldosterona; Animais; Canais Epiteliais de Sódio/genética; Canais Epiteliais de Sódio/metabolismo; Lipopolissacarídeos; Camundongos; Fosfatidilinositol 3-Quinases/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Transdução de Sinais

Palavras-chave

Acute lung injury; Aldosterone; CYP11B2; Epithelial sodium channel; PI3K/Akt/SGK1 pathway

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Canais Epiteliais de Sódio / Lesão Pulmonar Aguda Limite: Animals Idioma: En Revista: Mol Cell Probes Assunto da revista: BIOLOGIA MOLECULAR / BIOTECNOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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