Pyrazoles and Fused Pyrimidines: Synthesis, Structure Elucidation, Antitubercular Activity and Molecular Docking Study.

Al-Soliemy, Amerah M; Sabour, Rehab; Farghaly, Thoraya A

Al-Soliemy, Amerah M; Sabour, Rehab; Farghaly, Thoraya A.

Afiliação

Al-Soliemy AM; Department of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah, Saudi Arabia.
Sabour R; Department of Pharmaceutical Chemistry, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.
Farghaly TA; Department of Chemistry, Faculty of Science, University of Cairo, Giza 12613, Egypt.

Med Chem ; 18(2): 181-198, 2022.

Article em En | MEDLINE | ID: mdl-33761862

RESUMO

BACKGROUND: Synthesis of new heterocyclic drugs in short reaction time with sufficient quantity is considered as a target for several pharmaceutical scientists. Thus, organic reactions proceeded on the surface of nano-sized catalysts to speed up the stimulation process.

Assuntos

Pirazóis; Pirimidinas; Humanos; Testes de Sensibilidade Microbiana; Simulação de Acoplamento Molecular; Relação Estrutura-Atividade

Palavras-chave

Molecular docking; Pyazoles; antitubercular activity; enaminones; fused pyrimidines; hydrazonoyl halides

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Pirimidinas Limite: Humans Idioma: En Revista: Med Chem Assunto da revista: QUIMICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Arábia Saudita

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