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Interferon regulatory factor 1 (IRF-1) downregulates Checkpoint kinase 1 (CHK1) through miR-195 to upregulate apoptosis and PD-L1 expression in Hepatocellular carcinoma (HCC) cells.
Yan, Yihe; Zheng, Leting; Du, Qiang; Cui, Xiao; Dong, Kun; Guo, Yarong; Geller, David A.
Afiliação
  • Yan Y; Thomas E. Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. yiheyan@hotmail.com.
  • Zheng L; Department of General Surgery, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China. yiheyan@hotmail.com.
  • Du Q; Thomas E. Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
  • Cui X; Department of Rheumatology and Immunology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
  • Dong K; Thomas E. Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
  • Guo Y; Thomas E. Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
  • Geller DA; Thomas E. Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Br J Cancer ; 125(1): 101-111, 2021 07.
Article em En | MEDLINE | ID: mdl-33772151
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / MicroRNAs / Fator Regulador 1 de Interferon / Antígeno B7-H1 / Quinase 1 do Ponto de Checagem / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Br J Cancer Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / MicroRNAs / Fator Regulador 1 de Interferon / Antígeno B7-H1 / Quinase 1 do Ponto de Checagem / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Br J Cancer Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos