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Advancement of echocardiography for surveillance of iron overload cardiomyopathy: comparison to cardiac magnetic resonance imaging.
Zimmerman, M Jason; Rosing, Douglas R; Shizukuda, Yukitaka.
Afiliação
  • Zimmerman MJ; Appalachian Regional Healthcare, Highlands Regional Medical Center, Cardiovascular Associates, 5000 KY-321, Prestonsburg, KY, 41653, USA. Zimmerman_consulting@yahoo.com.
  • Rosing DR; Cardiovascular Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
  • Shizukuda Y; Cardiovascular Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
J Echocardiogr ; 19(3): 141-149, 2021 09.
Article em En | MEDLINE | ID: mdl-33772457
ABSTRACT
The prevalence of iron overload cardiomyopathy (IOC) is increasing. Patients with transfusion-dependent anemias or conditions associated with increased iron absorption over time are at a significant risk for the development of iron-overloaded states such as IOC. Current guidelines regarding the diagnostic evaluation and follow-up of patients at risk for IOC exist, and are composed of multiple components, including such as echocardiography, genetic testing, magnetic resonance imaging of liver, and cardiac magnetic resonance imaging (CMR). While these are considered reliable for the evaluation of patients at risk for an iron-overloaded state, there is an access challenge associated with initial and serial CMR scanning in this patient population. Furthermore, there are other limiting factors, such as patient characteristics that may preclude the use of CMR as a viable diagnostic imaging modality for these patients. On the other hand, recent evidence in the literature suggests that transthoracic echocardiography, which has had significant technological advances, can equal or even outperform CMR to identify cardiac functional abnormalities such as subclinical left ventricular strain and left atrial functional abnormalities in iron overload conditions. Therefore, there is a potential role of more frequent use of echocardiography for surveillance of the development of IOC. Our purpose with this narrative review is to describe recent advances in echocardiography and propose a potential increased use of echocardiography in the surveillance of the development of IOC.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sobrecarga de Ferro / Cardiomiopatias Tipo de estudo: Guideline / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Humans Idioma: En Revista: J Echocardiogr Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sobrecarga de Ferro / Cardiomiopatias Tipo de estudo: Guideline / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Humans Idioma: En Revista: J Echocardiogr Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos