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Discovery of sertraline and its derivatives able to combat drug-resistant gastric cancer cell via inducing apoptosis.
Mu, Chao; Peng, Rui-Kun; Guo, Chun-Ling; Li, Ao; Yang, Xiu-Ming; Zeng, Rong; Li, Yu-Long; Gu, Jing; Ouyang, Qin.
Afiliação
  • Mu C; College of Chemistry and Environmental Engineering, Sichuan University of Science and Engineering, Zigong 643000, China.
  • Peng RK; Department of Medicinal Chemistry, School of Pharmacy, Third Military Medical University, Chongqing 40038, China.
  • Guo CL; Department of Medicinal Chemistry, School of Pharmacy, Third Military Medical University, Chongqing 40038, China.
  • Li A; College of Chemistry and Environmental Engineering, Sichuan University of Science and Engineering, Zigong 643000, China.
  • Yang XM; Department of Medicinal Chemistry, School of Pharmacy, Third Military Medical University, Chongqing 40038, China.
  • Zeng R; Department of Medicinal Chemistry, School of Pharmacy, Third Military Medical University, Chongqing 40038, China.
  • Li YL; College of Chemistry and Environmental Engineering, Sichuan University of Science and Engineering, Zigong 643000, China. Electronic address: yu_longli@aliyun.com.
  • Gu J; Department of Medicinal Chemistry, School of Pharmacy, Third Military Medical University, Chongqing 40038, China. Electronic address: gujing_1020@126.com.
  • Ouyang Q; Department of Medicinal Chemistry, School of Pharmacy, Third Military Medical University, Chongqing 40038, China. Electronic address: ouyangq@tmmu.edu.cn.
Bioorg Med Chem Lett ; 41: 127997, 2021 06 01.
Article em En | MEDLINE | ID: mdl-33775839
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Apoptose / Resistencia a Medicamentos Antineoplásicos / Sertralina / Descoberta de Drogas / Antineoplásicos Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Apoptose / Resistencia a Medicamentos Antineoplásicos / Sertralina / Descoberta de Drogas / Antineoplásicos Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China