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Epigenetic silencing of GCH1promotes hepatocellular carcinoma growth by activating superoxide anion-mediated ASK1/p38 signaling via inhibiting tetrahydrobiopterin de novo biosynthesis.
Zhong, Guo-Chao; Zhao, Zhi-Bo; Cheng, Yao; Wang, Yun-Bing; Qiu, Chan; Mao, Lin-Hong; Hu, Jie-Jun; Cai, Dong; Liu, Yan; Gong, Jian-Ping; Li, Sheng-Wei.
Afiliação
  • Zhong GC; Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Zhao ZB; Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Cheng Y; Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Wang YB; Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Qiu C; Department of Gastroenterology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Mao LH; Department of Gastroenterology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Hu JJ; Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Cai D; Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Liu Y; Department of Gastroenterology, The Fifth People's Hospital of Chengdu, Chengdu, China.
  • Gong JP; Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China. Electronic address: gongjianping@cqmu.edu.cn.
  • Li SW; Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China. Electronic address: 2010210058@stu.cqmu.edu.cn.
Free Radic Biol Med ; 168: 81-94, 2021 05 20.
Article em En | MEDLINE | ID: mdl-33781891
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Neoplasias Hepáticas Limite: Humans Idioma: En Revista: Free Radic Biol Med Assunto da revista: BIOQUIMICA / MEDICINA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Neoplasias Hepáticas Limite: Humans Idioma: En Revista: Free Radic Biol Med Assunto da revista: BIOQUIMICA / MEDICINA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China