ASHLEYS: automated quality control for single-cell Strand-seq data.
Bioinformatics
; 37(19): 3356-3357, 2021 Oct 11.
Article
em En
| MEDLINE
| ID: mdl-33792647
ABSTRACT
SUMMARY:
Single-cell DNA template strand sequencing (Strand-seq) enables chromosome length haplotype phasing, construction of phased assemblies, mapping sister-chromatid exchange events and structural variant discovery. The initial quality control of potentially thousands of single-cell libraries is still done manually by domain experts. ASHLEYS automates this tedious task, delivers near-expert performance and labels even large datasets in seconds. AVAILABILITY AND IMPLEMENTATION github.com/friendsofstrandseq/ashleys-qc, MIT license. SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Bioinformatics
Assunto da revista:
INFORMATICA MEDICA
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Alemanha