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Mutations in BRCA1 and BRCA2 differentially affect the tumor microenvironment and response to checkpoint blockade immunotherapy.
Samstein, Robert M; Krishna, Chirag; Ma, Xiaoxiao; Pei, Xin; Lee, Ken-Wing; Makarov, Vladimir; Kuo, Fengshen; Chung, Jonathan; Srivastava, Raghvendra M; Purohit, Tanaya A; Hoen, Douglas R; Mandal, Rajarsi; Setton, Jeremy; Wu, Wei; Shah, Rachna; Qeriqi, Besnik; Chang, Qing; Kendall, Sviatoslav; Braunstein, Lior; Weigelt, Britta; Blecua Carrillo Albornoz, Pedro; Morris, Luc G T; Mandelker, Diana L; Reis-Filho, Jorge S; de Stanchina, Elisa; Powell, Simon N; Chan, Timothy A; Riaz, Nadeem.
Afiliação
  • Samstein RM; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Krishna C; Department of Radiation Oncology, Mount Sinai Hospital, New York, NY, USA.
  • Ma X; Precision Immunology Institute at Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Pei X; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Lee KW; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Makarov V; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Kuo F; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Chung J; Immunogenomics and Precision Oncology Platform, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Srivastava RM; Immunogenomics and Precision Oncology Platform, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Purohit TA; Precision Immunology Institute at Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Hoen DR; Immunogenomics and Precision Oncology Platform, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Mandal R; Immunogenomics and Precision Oncology Platform, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Setton J; Immunogenomics and Precision Oncology Platform, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Wu W; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Shah R; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Qeriqi B; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Chang Q; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Kendall S; Antitumor Assessment Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Braunstein L; Antitumor Assessment Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Weigelt B; Immunogenomics and Precision Oncology Platform, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Blecua Carrillo Albornoz P; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Morris LGT; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Mandelker DL; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Reis-Filho JS; Cancer and Leukemia Epigenetics and Biology Program, Josep Carreras Leukaemia Research Institute, Barcelona, Spain.
  • de Stanchina E; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Powell SN; Immunogenomics and Precision Oncology Platform, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Chan TA; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Riaz N; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Nat Cancer ; 1(12): 1188-1203, 2021 12.
Article em En | MEDLINE | ID: mdl-33834176
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Microambiente Tumoral / Inibidores de Checkpoint Imunológico / Neoplasias Limite: Animals / Humans Idioma: En Revista: Nat Cancer Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Microambiente Tumoral / Inibidores de Checkpoint Imunológico / Neoplasias Limite: Animals / Humans Idioma: En Revista: Nat Cancer Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos