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A small molecule inhibitor of the chloride channel TMEM16A blocks vascular smooth muscle contraction and lowers blood pressure in spontaneously hypertensive rats.
Cil, Onur; Chen, Xiaolan; Askew Page, Henry R; Baldwin, Samuel N; Jordan, Maria C; Myat Thwe, Pyone; Anderson, Marc O; Haggie, Peter M; Greenwood, Iain A; Roos, Kenneth P; Verkman, Alan S.
Afiliação
  • Cil O; Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA. Electronic address: onur.cil@ucsf.edu.
  • Chen X; Department of Medicine, University of California, San Francisco, San Francisco, California, USA; Department of Physiology, University of California, San Francisco, San Francisco, California, USA.
  • Askew Page HR; Vascular Biology Research Centre, Institute of Molecular and Clinical Sciences, St. George's University of London, London, UK.
  • Baldwin SN; Vascular Biology Research Centre, Institute of Molecular and Clinical Sciences, St. George's University of London, London, UK.
  • Jordan MC; Department of Physiology, University of California, Los Angeles, Los Angeles, California, USA.
  • Myat Thwe P; Department of Chemistry and Biochemistry, San Francisco State University, San Francisco, California, USA.
  • Anderson MO; Department of Chemistry and Biochemistry, San Francisco State University, San Francisco, California, USA.
  • Haggie PM; Department of Medicine, University of California, San Francisco, San Francisco, California, USA; Department of Physiology, University of California, San Francisco, San Francisco, California, USA.
  • Greenwood IA; Vascular Biology Research Centre, Institute of Molecular and Clinical Sciences, St. George's University of London, London, UK.
  • Roos KP; Department of Physiology, University of California, Los Angeles, Los Angeles, California, USA.
  • Verkman AS; Department of Medicine, University of California, San Francisco, San Francisco, California, USA; Department of Physiology, University of California, San Francisco, San Francisco, California, USA.
Kidney Int ; 100(2): 311-320, 2021 08.
Article em En | MEDLINE | ID: mdl-33836171
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vasoconstrição / Anoctamina-1 / Hipertensão / Músculo Liso Vascular Limite: Animals Idioma: En Revista: Kidney Int Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vasoconstrição / Anoctamina-1 / Hipertensão / Músculo Liso Vascular Limite: Animals Idioma: En Revista: Kidney Int Ano de publicação: 2021 Tipo de documento: Article