Effects of a Mindfulness-Based Intervention versus Health Self-Management on Subclinical Anxiety in Older Adults with Subjective Cognitive Decline: The SCD-Well Randomized Superiority Trial.
Psychother Psychosom
; 90(5): 341-350, 2021.
Article
em En
| MEDLINE
| ID: mdl-33873195
ABSTRACT
INTRODUCTION:
Older adults experiencing subjective cognitive decline (SCD) have a heightened risk of developing dementia and frequently experience subclinical anxiety, which is itself associated with dementia risk.OBJECTIVE:
To understand whether subclinical anxiety symptoms in SCD can be reduced through behavioral interventions.METHODS:
SCD-Well is a randomized controlled trial designed to determine whether an 8-week mindfulness-based intervention (caring mindfulness-based approach for seniors; CMBAS) is superior to a structurally matched health self-management program (HSMP) in reducing subclinical anxiety. Participants were recruited from memory clinics at 4 European sites. The primary outcome was change in anxiety symptoms (trait subscale of the State-Trait Anxiety Inventory; trait-STAI) from pre- to postintervention. Secondary outcomes included a change in state anxiety and depression symptoms postintervention and 6 months postrandomization (follow-up).RESULTS:
One hundred forty-seven participants (mean [SD] age 72.7 [6.9] years; 64.6% women; CMBAS, n = 73; HSMP, n = 74) were included in the intention-to-treat analysis. There was no difference in trait-STAI between groups postintervention (adjusted change difference -1.25 points; 95% CI -4.76 to 2.25) or at follow-up (adjusted change difference -0.43 points; 95% CI -2.92 to 2.07). Trait-STAI decreased postintervention in both groups (CMBAS -3.43 points; 95% CI -5.27 to -1.59; HSMP -2.29 points; 95% CI -4.14 to -0.44) and reductions were maintained at follow-up. No between-group differences were observed for change in state anxiety or depression symptoms.CONCLUSIONS:
A time-limited mindfulness intervention is not superior to health self-management in reducing subclinical anxiety symptoms in SCD. The sustained reduction observed across both groups suggests that subclinical anxiety symptoms in SCD are modifiable. ClinicalTrials.gov identifier NCT03005652.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Disfunção Cognitiva
/
Atenção Plena
/
Autogestão
Tipo de estudo:
Clinical_trials
Limite:
Aged
/
Female
/
Humans
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Male
Idioma:
En
Revista:
Psychother Psychosom
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Reino Unido