Cytoplasmic polyadenylation by TENT5A is required for proper bone formation.

Gewartowska, Olga; Aranaz-Novaliches, Goretti; Krawczyk, Pawel S; Mroczek, Seweryn; Kusio-Kobialka, Monika; Tarkowski, Bartosz; Spoutil, Frantisek; Benada, Oldrich; Kofronová, Olga; Szwedziak, Piotr; Cysewski, Dominik; Gruchota, Jakub; Szpila, Marcin; Chlebowski, Aleksander; Sedlacek, Radislav; Prochazka, Jan; Dziembowski, Andrzej

Gewartowska, Olga; Aranaz-Novaliches, Goretti; Krawczyk, Pawel S; Mroczek, Seweryn; Kusio-Kobialka, Monika; Tarkowski, Bartosz; Spoutil, Frantisek; Benada, Oldrich; Kofronová, Olga; Szwedziak, Piotr; Cysewski, Dominik; Gruchota, Jakub; Szpila, Marcin; Chlebowski, Aleksander; Sedlacek, Radislav; Prochazka, Jan; Dziembowski, Andrzej.

Afiliação

Gewartowska O; Laboratory of RNA Biology, International Institute of Molecular and Cell Biology in Warsaw, Trojdena 4, 02-109 Warsaw, Poland; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland; Institute of Genetics and Biotechnology, Faculty of Biology, Uni
Aranaz-Novaliches G; Laboratory of Transgenic Models of Diseases, Institute of Molecular Genetics of the Czech Academy of Sciences, v.v.i., 142 20 Prague 4, Czech Republic.
Krawczyk PS; Laboratory of RNA Biology, International Institute of Molecular and Cell Biology in Warsaw, Trojdena 4, 02-109 Warsaw, Poland; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland.
Mroczek S; Laboratory of RNA Biology, International Institute of Molecular and Cell Biology in Warsaw, Trojdena 4, 02-109 Warsaw, Poland; Institute of Genetics and Biotechnology, Faculty of Biology, University of Warsaw, Pawinskiego 5a, 02-106 Warsaw, Poland.
Kusio-Kobialka M; Laboratory of RNA Biology, International Institute of Molecular and Cell Biology in Warsaw, Trojdena 4, 02-109 Warsaw, Poland; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland; Institute of Genetics and Biotechnology, Faculty of Biology, Uni
Tarkowski B; Laboratory of RNA Biology, International Institute of Molecular and Cell Biology in Warsaw, Trojdena 4, 02-109 Warsaw, Poland; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland.
Spoutil F; Laboratory of Transgenic Models of Diseases, Institute of Molecular Genetics of the Czech Academy of Sciences, v.v.i., 142 20 Prague 4, Czech Republic; Czech Centre for Phenogenomics, Institute of Molecular Genetics of the CAS, Prague, Czech Republic.
Benada O; Institute of Microbiology of the Czech Academy of Sciences, v.v.i., 142 20 Prague 4, Czech Republic.
Kofronová O; Institute of Microbiology of the Czech Academy of Sciences, v.v.i., 142 20 Prague 4, Czech Republic.
Szwedziak P; Laboratory of Structural Cell Biology, Centre of New Technologies, University of Warsaw, 02-097 Warsaw, Poland; ReMedy-International Research Agenda Unit, Centre of New Technologies, University of Warsaw, 02-097 Warsaw, Poland.
Cysewski D; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland.
Gruchota J; Laboratory of RNA Biology, International Institute of Molecular and Cell Biology in Warsaw, Trojdena 4, 02-109 Warsaw, Poland; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland.
Szpila M; Laboratory of RNA Biology, International Institute of Molecular and Cell Biology in Warsaw, Trojdena 4, 02-109 Warsaw, Poland; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland.
Chlebowski A; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland.
Sedlacek R; Laboratory of Transgenic Models of Diseases, Institute of Molecular Genetics of the Czech Academy of Sciences, v.v.i., 142 20 Prague 4, Czech Republic; Czech Centre for Phenogenomics, Institute of Molecular Genetics of the CAS, Prague, Czech Republic.
Prochazka J; Laboratory of Transgenic Models of Diseases, Institute of Molecular Genetics of the Czech Academy of Sciences, v.v.i., 142 20 Prague 4, Czech Republic; Czech Centre for Phenogenomics, Institute of Molecular Genetics of the CAS, Prague, Czech Republic.
Dziembowski A; Laboratory of RNA Biology, International Institute of Molecular and Cell Biology in Warsaw, Trojdena 4, 02-109 Warsaw, Poland; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland; Institute of Genetics and Biotechnology, Faculty of Biology, Uni

Cell Rep ; 35(3): 109015, 2021 04 20.

Article em En | MEDLINE | ID: mdl-33882302

Assuntos

Calcificação Fisiológica/genética; Osteoblastos/metabolismo; Osteogênese Imperfeita/genética; Osteogênese/genética; Polinucleotídeo Adenililtransferase/genética; RNA Mensageiro/genética; Animais; Diferenciação Celular; Colágeno Tipo I/genética; Colágeno Tipo I/metabolismo; Cadeia alfa 1 do Colágeno Tipo I/genética; Cadeia alfa 1 do Colágeno Tipo I/metabolismo; Modelos Animais de Doenças; Proteínas do Olho/genética; Proteínas do Olho/metabolismo; Feminino; Regulação da Expressão Gênica no Desenvolvimento; Humanos; Masculino; Camundongos; Camundongos Knockout; Fatores de Crescimento Neural/genética; Fatores de Crescimento Neural/metabolismo; Nucleotidiltransferases/genética; Nucleotidiltransferases/metabolismo; Osteoblastos/patologia; Osteogênese Imperfeita/metabolismo; Osteogênese Imperfeita/patologia; Osteonectina/genética; Osteonectina/metabolismo; Poliadenilação; Polinucleotídeo Adenililtransferase/metabolismo; Isoformas de Proteínas/deficiência; Isoformas de Proteínas/genética; RNA Mensageiro/metabolismo; Análise de Sequência de RNA; Serpinas/genética; Serpinas/metabolismo; Transdução de Sinais

Palavras-chave

FAM46A; Nanopore; TENT5A; collagen; direct RNA sequencing; osteoblasts; osteogenesis; osteogenesis imperfecta; poly(A) tail; polyadenylation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoblastos / Osteogênese / Osteogênese Imperfeita / Polinucleotídeo Adenililtransferase / Calcificação Fisiológica / RNA Mensageiro Tipo de estudo: Prognostic_studies / Qualitative_research Idioma: En Revista: Cell Rep Ano de publicação: 2021 Tipo de documento: Article

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