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FT-4202, an oral PKR activator, has potent antisickling effects and improves RBC survival and Hb levels in SCA mice.
Shrestha, Archana; Chi, Mengna; Wagner, Kimberly; Malik, Astha; Korpik, Jennifer; Drake, Adam; Fulzele, Keertik; Guichard, Sylvie; Malik, Punam.
Afiliação
  • Shrestha A; Division of Experimental Hematology and Cancer Biology.
  • Chi M; Division of Experimental Hematology and Cancer Biology.
  • Wagner K; Division of Experimental Hematology and Cancer Biology.
  • Malik A; Division of Gastroenterology, Hepatology and Nutrition, and.
  • Korpik J; Erythrocyte Diagnostic Laboratory, Cancer and Blood Diseases Institute (CBDI), Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, OH.
  • Drake A; FORMA Therapeutics, Inc, Watertown, MA; and.
  • Fulzele K; FORMA Therapeutics, Inc, Watertown, MA; and.
  • Guichard S; FORMA Therapeutics, Inc, Watertown, MA; and.
  • Malik P; Division of Experimental Hematology and Cancer Biology.
Blood Adv ; 5(9): 2385-2390, 2021 05 11.
Article em En | MEDLINE | ID: mdl-33944896
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hemoglobina Falciforme / Anemia Falciforme Limite: Animals / Humans Idioma: En Revista: Blood Adv Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hemoglobina Falciforme / Anemia Falciforme Limite: Animals / Humans Idioma: En Revista: Blood Adv Ano de publicação: 2021 Tipo de documento: Article