CM1-driven assembly and activation of yeast Î³-tubulin small complex underlies microtubule nucleation.

Brilot, Axel F; Lyon, Andrew S; Zelter, Alex; Viswanath, Shruthi; Maxwell, Alison; MacCoss, Michael J; Muller, Eric G; Sali, Andrej; Davis, Trisha N; Agard, David A

Brilot, Axel F; Lyon, Andrew S; Zelter, Alex; Viswanath, Shruthi; Maxwell, Alison; MacCoss, Michael J; Muller, Eric G; Sali, Andrej; Davis, Trisha N; Agard, David A.

Afiliação

Brilot AF; Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, United States.
Lyon AS; Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, United States.
Zelter A; Department of Biochemistry, University of Washington, Seattle, United States.
Viswanath S; Department of Bioengineering and Therapeutic Sciences, University of California at San Francisco, San Francisco, United States.
Maxwell A; Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, United States.
MacCoss MJ; Department of Genome Sciences, University of Washington, Seattle, United States.
Muller EG; Department of Biochemistry, University of Washington, Seattle, United States.
Sali A; Department of Bioengineering and Therapeutic Sciences, University of California at San Francisco, San Francisco, United States.
Davis TN; Department of Biochemistry, University of Washington, Seattle, United States.
Agard DA; Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, United States.

Elife ; 102021 05 05.

Article em En | MEDLINE | ID: mdl-33949948

Assuntos

Antígenos Nucleares/genética; Microtúbulos/fisiologia; Saccharomyces cerevisiae/genética; Saccharomyces cerevisiae/metabolismo; Tubulina (Proteína)/química; Tubulina (Proteína)/genética; Sítios de Ligação; Proteínas de Ligação a Calmodulina/genética; Proteínas de Ligação a Calmodulina/metabolismo; Microscopia Crioeletrônica/métodos; Cristalografia por Raios X/métodos; Proteínas do Citoesqueleto/genética; Proteínas do Citoesqueleto/metabolismo; Humanos; Espectrometria de Massas/métodos; Centro Organizador dos Microtúbulos; Proteínas de Saccharomyces cerevisiae/genética; Proteínas de Saccharomyces cerevisiae/metabolismo; Tubulina (Proteína)/classificação; Tubulina (Proteína)/metabolismo

Palavras-chave

S. cerevisiae; cell biology; cytoskeleton; electron microscopy; microtubule nucleation; molecular biophysics; structural biology

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / Tubulina (Proteína) / Antígenos Nucleares / Microtúbulos Limite: Humans Idioma: En Revista: Elife Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

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