LncRNA HOTAIR regulates the expression of E-cadherin to affect nasopharyngeal carcinoma progression by recruiting histone methylase EZH2 to mediate H3K27 trimethylation.

Yang, Feng-Lian; Wei, Yu-Xia; Liao, Bi-Yun; Wei, Gui-Jiang; Qin, Hai-Mei; Pang, Xiao-Xia; Wang, Jun-Li

Yang, Feng-Lian; Wei, Yu-Xia; Liao, Bi-Yun; Wei, Gui-Jiang; Qin, Hai-Mei; Pang, Xiao-Xia; Wang, Jun-Li.

Afiliação

Yang FL; Youjiang Medical University for Nationalities, Baise 533000, Guangxi, China.
Wei YX; Center of Reproductive and Genetic Medicine, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise 533000, Guangxi, China.
Liao BY; Center of Reproductive and Genetic Medicine, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise 533000, Guangxi, China.
Wei GJ; Center of Reproductive and Genetic Medicine, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise 533000, Guangxi, China.
Qin HM; Center of Reproductive and Genetic Medicine, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise 533000, Guangxi, China.
Pang XX; Center of Reproductive and Genetic Medicine, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise 533000, Guangxi, China.
Wang JL; Center of Reproductive and Genetic Medicine, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise 533000, Guangxi, China. Electronic address: baisewangjunli@126.com.

Genomics ; 113(4): 2276-2289, 2021 07.

Article em En | MEDLINE | ID: mdl-33965547

Assuntos

Neoplasias Nasofaríngeas; RNA Longo não Codificante; Caderinas/genética; Caderinas/metabolismo; Linhagem Celular Tumoral; Proteína Potenciadora do Homólogo 2 de Zeste/genética; Proteína Potenciadora do Homólogo 2 de Zeste/metabolismo; Regulação Neoplásica da Expressão Gênica; Histona Metiltransferases/genética; Histona Metiltransferases/metabolismo; Humanos; Carcinoma Nasofaríngeo/genética; Neoplasias Nasofaríngeas/genética; RNA Longo não Codificante/genética; RNA Longo não Codificante/metabolismo

Palavras-chave

E-cadherin; EZH2; H3K27me3; LncRNA HOTAIR; Nasopharyngeal carcinoma

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Nasofaríngeas / RNA Longo não Codificante Limite: Humans Idioma: En Revista: Genomics Assunto da revista: GENETICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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