A New Application of MALDI Biotyper for a Potential Use in Therapeutic Drug Monitoring of Voriconazole.
Antimicrob Agents Chemother
; 65(8): e0245820, 2021 07 16.
Article
em En
| MEDLINE
| ID: mdl-33972255
ABSTRACT
We present a proof-of-concept study on the use of MALDI Biotyper to detect and monitor the levels of voriconazole in human serum. A simple extraction-concentration method and a MALDI Biotyper protocol were developed, and a parent ion of voriconazole (1 H+) could be detected and quantified with good reproducibility. Our results point to a new application of MALDI Biotyper for therapeutic drug monitoring.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Monitoramento de Medicamentos
Tipo de estudo:
Guideline
Limite:
Humans
Idioma:
En
Revista:
Antimicrob Agents Chemother
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Espanha