Targeting the Gut Microbiota for Remediating Obesity and Related Metabolic Disorders.
J Nutr
; 151(7): 1703-1716, 2021 07 01.
Article
em En
| MEDLINE
| ID: mdl-33982127
ABSTRACT
The rate of obesity is rapidly increasing and has become a health and economic burden worldwide. As recent studies have revealed that the gut microbiota is closely linked to obesity, researchers have used various approaches to modulate the gut microbiota to treat the condition. Dietary composition and energy intake strongly affect the composition and function of the gut microbiota. Intestinal microbial changes alter the composition of bile acids and fatty acids and regulate bacterial lipopolysaccharide production, all of which influence energy metabolism and immunity. Evidence also suggests that remodeling the gut microbiota through intake of probiotics, prebiotics, fermented foods, and dietary plants, as well as by fecal microbiota transplantation, are feasible methods to remediate obesity.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Probióticos
/
Microbioma Gastrointestinal
/
Doenças Metabólicas
Limite:
Humans
Idioma:
En
Revista:
J Nutr
Ano de publicação:
2021
Tipo de documento:
Article