Factors associated with COVID-19 in people with Parkinson's disease: a systematic review and meta-analysis.
Eur J Neurol
; 28(10): 3467-3477, 2021 Oct.
Article
em En
| MEDLINE
| ID: mdl-33983673
ABSTRACT
BACKGROUND:
There is debate as to whether there is an increased risk of COVID-19 infection in people with Parkinson's disease (PD), possibly due to associated factors. This study aimed to systematically review the factors associated with COVID-19 in people with PD.METHODS:
A search was carried out in PubMed, Scopus, and Web of Science up to November 2020 (updated until 1 April 2021). Observational studies that analyzed factors associated with COVID-19 in people with PD were selected and revised.RESULTS:
The authors included six studies (four case-controlled studies and two cross-sectional studies) in the qualitative and quantitative syntheses. The authors found that the following factors were associated with COVID-19 in people with PD obesity (OR 1.79, 95% CI 1.07-2.99, I2 0%), any pulmonary disease (OR 1.92, 95% CI 1.17-3.15, I2 0%), COVID-19 contact (OR 41.77, 95% CI 4.77 - 365.56, I2 0%), vitamin D supplementation (OR 0.50, 95% CI 0.30-0.83, I2 0%), hospitalization (OR 11.78, 95% CI 6.27-22.12, I2 0%), and death (OR 11.23, 95% CI 3.92-32.18, I2 0%). The authors did not find any significant association between COVID-19 and hypertension, diabetes, cardiopathy, cancer, any cognitive problem, dementia, chronic obstructive pulmonary disease, renal or hepatic disease, smoking, and tremor.CONCLUSIONS:
Meta-analyses were limited by the number of events and some methodological limitations. Despite this, the authors assessed the available evidence, and the results may be useful for future health policies.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doença de Parkinson
/
Diabetes Mellitus
/
COVID-19
Tipo de estudo:
Observational_studies
/
Prevalence_studies
/
Qualitative_research
/
Risk_factors_studies
/
Systematic_reviews
Limite:
Humans
Idioma:
En
Revista:
Eur J Neurol
Assunto da revista:
NEUROLOGIA
Ano de publicação:
2021
Tipo de documento:
Article