Outer membrane and phospholipid composition of the target membrane affect the antimicrobial potential of first- and second-generation lipophosphonoxins.

Látrová, Klára; Havlová, Noemi; Vecerová, Renata; Pinkas, Dominik; Bogdanová, Katerina; Kolár, Milan; Fiser, Radovan; Konopásek, Ivo; Do Pham, Duy Dinh; Rejman, Dominik; Mikusová, Gabriela

Látrová, Klára; Havlová, Noemi; Vecerová, Renata; Pinkas, Dominik; Bogdanová, Katerina; Kolár, Milan; Fiser, Radovan; Konopásek, Ivo; Do Pham, Duy Dinh; Rejman, Dominik; Mikusová, Gabriela.

Afiliação

Látrová K; Department of Genetics and Microbiology, Faculty of Science, Charles University, Vinicná 5, 128 00, Prague 2, Czech Republic.
Havlová N; Department of Genetics and Microbiology, Faculty of Science, Charles University, Vinicná 5, 128 00, Prague 2, Czech Republic.
Vecerová R; Department of Microbiology, Faculty of Medicine and Dentistry, Palacký University Olomouc, Hnevotínská 3, 775 15, Olomouc, Czech Republic.
Pinkas D; Department of Genetics and Microbiology, Faculty of Science, Charles University, Vinicná 5, 128 00, Prague 2, Czech Republic.
Bogdanová K; Department of Microbiology, Faculty of Medicine and Dentistry, Palacký University Olomouc, Hnevotínská 3, 775 15, Olomouc, Czech Republic.
Kolár M; Department of Microbiology, Faculty of Medicine and Dentistry, Palacký University Olomouc, Hnevotínská 3, 775 15, Olomouc, Czech Republic.
Fiser R; Department of Genetics and Microbiology, Faculty of Science, Charles University, Vinicná 5, 128 00, Prague 2, Czech Republic.
Konopásek I; Department of Genetics and Microbiology, Faculty of Science, Charles University, Vinicná 5, 128 00, Prague 2, Czech Republic.
Do Pham DD; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences v.v.i., Flemingovo nám. 2, 166 10, Prague 6, Czech Republic.
Rejman D; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences v.v.i., Flemingovo nám. 2, 166 10, Prague 6, Czech Republic. rejman@uochb.cas.cz.
Mikusová G; Department of Genetics and Microbiology, Faculty of Science, Charles University, Vinicná 5, 128 00, Prague 2, Czech Republic. seydlova@natur.cuni.cz.

Sci Rep ; 11(1): 10446, 2021 05 17.

Article em En | MEDLINE | ID: mdl-34001940

Assuntos

Antibacterianos/farmacologia; Peptídeos Catiônicos Antimicrobianos/farmacologia; Bacillus subtilis/efeitos dos fármacos; Membrana Externa Bacteriana/efeitos dos fármacos; Escherichia coli/efeitos dos fármacos; Antibacterianos/síntese química; Peptídeos Catiônicos Antimicrobianos/síntese química; Bacillus subtilis/química; Bacillus subtilis/citologia; Membrana Externa Bacteriana/química; Membrana Externa Bacteriana/metabolismo; Permeabilidade da Membrana Celular; Escherichia coli/química; Escherichia coli/citologia; Bicamadas Lipídicas; Potenciais da Membrana/efeitos dos fármacos; Testes de Sensibilidade Microbiana; Fosfatidilcolinas/análise; Fosfatidilcolinas/metabolismo; Fosfatidiletanolaminas/análise; Fosfatidiletanolaminas/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bacillus subtilis / Peptídeos Catiônicos Antimicrobianos / Escherichia coli / Membrana Externa Bacteriana / Antibacterianos Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: República Tcheca

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