FGF-2 suppresses neuronal autophagy by regulating the PI3K/Akt pathway in subarachnoid hemorrhage.

Wang, Yue; Pan, Xiao-Fei; Liu, Guo-Dong; Liu, Zhuang-Hua; Zhang, Can; Chen, Tao; Wang, Yu-Hai

Wang, Yue; Pan, Xiao-Fei; Liu, Guo-Dong; Liu, Zhuang-Hua; Zhang, Can; Chen, Tao; Wang, Yu-Hai.

Afiliação

Wang Y; Department of Neurosurgery, Wuxi Clinical College of Anhui Medical University (The 904th Hospital of PLA), Wuxi, Jiangsu Province, 214044, China.
Pan XF; Department of Neurosurgery, Wuxi Clinical College of Anhui Medical University (The 904th Hospital of PLA), Wuxi, Jiangsu Province, 214044, China.
Liu GD; Department of Neurosurgery, Wuxi Clinical College of Anhui Medical University (The 904th Hospital of PLA), Wuxi, Jiangsu Province, 214044, China.
Liu ZH; Department of Neurosurgery, Wuxi Clinical College of Anhui Medical University (The 904th Hospital of PLA), Wuxi, Jiangsu Province, 214044, China.
Zhang C; Department of Neurosurgery, Wuxi Clinical College of Anhui Medical University (The 904th Hospital of PLA), Wuxi, Jiangsu Province, 214044, China.
Chen T; Department of Neurosurgery, Wuxi Clinical College of Anhui Medical University (The 904th Hospital of PLA), Wuxi, Jiangsu Province, 214044, China. Electronic address: fmmuchentao@163.com.
Wang YH; Department of Neurosurgery, Wuxi Clinical College of Anhui Medical University (The 904th Hospital of PLA), Wuxi, Jiangsu Province, 214044, China. Electronic address: prof_wyh101@163.com.

Brain Res Bull ; 173: 132-140, 2021 08.

Article em En | MEDLINE | ID: mdl-34023434

Assuntos

Autofagia/efeitos dos fármacos; Fator 2 de Crescimento de Fibroblastos/farmacologia; Neurônios/efeitos dos fármacos; Fármacos Neuroprotetores/farmacologia; Transdução de Sinais/efeitos dos fármacos; Hemorragia Subaracnóidea/metabolismo; Animais; Encéfalo/efeitos dos fármacos; Encéfalo/metabolismo; Masculino; Neurônios/metabolismo; Fosfatidilinositol 3-Quinases/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Ratos; Ratos Sprague-Dawley

Palavras-chave

Autophagy; Early brain injury; Fibroblast growth factor-2; PI3K/Akt; Subarachnoid hemorrhage

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Hemorragia Subaracnóidea / Transdução de Sinais / Fator 2 de Crescimento de Fibroblastos / Fármacos Neuroprotetores / Neurônios Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Brain Res Bull Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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