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FLT3 tyrosine kinase inhibitors synergize with BCL-2 inhibition to eliminate FLT3/ITD acute leukemia cells through BIM activation.
Zhu, Ruiqi; Li, Li; Nguyen, Bao; Seo, Jaesung; Wu, Min; Seale, Tessa; Levis, Mark; Duffield, Amy; Hu, Yu; Small, Donald.
Afiliação
  • Zhu R; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Li L; Department of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Nguyen B; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Seo J; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Wu M; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Seale T; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Levis M; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Duffield A; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Hu Y; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Small D; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Signal Transduct Target Ther ; 6(1): 186, 2021 05 24.
Article em En | MEDLINE | ID: mdl-34024909
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Leucemia Mieloide Aguda / Compostos Bicíclicos Heterocíclicos com Pontes / Proteínas Proto-Oncogênicas c-bcl-2 / Inibidores de Proteínas Quinases / Tirosina Quinase 3 Semelhante a fms / Proteína 11 Semelhante a Bcl-2 / Sorafenibe Limite: Humans Idioma: En Revista: Signal Transduct Target Ther Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Leucemia Mieloide Aguda / Compostos Bicíclicos Heterocíclicos com Pontes / Proteínas Proto-Oncogênicas c-bcl-2 / Inibidores de Proteínas Quinases / Tirosina Quinase 3 Semelhante a fms / Proteína 11 Semelhante a Bcl-2 / Sorafenibe Limite: Humans Idioma: En Revista: Signal Transduct Target Ther Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos