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Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer's disease.
Walgrave, Hannah; Balusu, Sriram; Snoeck, Sarah; Vanden Eynden, Elke; Craessaerts, Katleen; Thrupp, Nicky; Wolfs, Leen; Horré, Katrien; Fourne, Yannick; Ronisz, Alicja; Silajdzic, Edina; Penning, Amber; Tosoni, Giorgia; Callaerts-Vegh, Zsuzsanna; D'Hooge, Rudi; Thal, Dietmar Rudolf; Zetterberg, Henrik; Thuret, Sandrine; Fiers, Mark; Frigerio, Carlo Sala; De Strooper, Bart; Salta, Evgenia.
Afiliação
  • Walgrave H; VIB Center for Brain & Disease Research, 3000 Leuven, Belgium; KU Leuven, Leuven Brain Institute, 3000 Leuven, Belgium.
  • Balusu S; VIB Center for Brain & Disease Research, 3000 Leuven, Belgium; KU Leuven, Leuven Brain Institute, 3000 Leuven, Belgium.
  • Snoeck S; Laboratory of Neurogenesis and Neurodegeneration, Netherlands Institute for Neuroscience, 1105BA Amsterdam, the Netherlands.
  • Vanden Eynden E; VIB Center for Brain & Disease Research, 3000 Leuven, Belgium; KU Leuven, Leuven Brain Institute, 3000 Leuven, Belgium.
  • Craessaerts K; VIB Center for Brain & Disease Research, 3000 Leuven, Belgium; KU Leuven, Leuven Brain Institute, 3000 Leuven, Belgium.
  • Thrupp N; VIB Center for Brain & Disease Research, 3000 Leuven, Belgium; KU Leuven, Leuven Brain Institute, 3000 Leuven, Belgium.
  • Wolfs L; VIB Center for Brain & Disease Research, 3000 Leuven, Belgium; KU Leuven, Leuven Brain Institute, 3000 Leuven, Belgium.
  • Horré K; VIB Center for Brain & Disease Research, 3000 Leuven, Belgium; KU Leuven, Leuven Brain Institute, 3000 Leuven, Belgium.
  • Fourne Y; VIB Center for Brain & Disease Research, 3000 Leuven, Belgium; KU Leuven, Leuven Brain Institute, 3000 Leuven, Belgium.
  • Ronisz A; KU Leuven, Leuven Brain Institute, 3000 Leuven, Belgium; Laboratory for Neuropathology, KU Leuven, and Department of Pathology, UZ Leuven, 3000 Leuven, Belgium.
  • Silajdzic E; Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 9RX, UK.
  • Penning A; Laboratory of Neurogenesis and Neurodegeneration, Netherlands Institute for Neuroscience, 1105BA Amsterdam, the Netherlands.
  • Tosoni G; Laboratory of Neurogenesis and Neurodegeneration, Netherlands Institute for Neuroscience, 1105BA Amsterdam, the Netherlands.
  • Callaerts-Vegh Z; KU Leuven, Leuven Brain Institute, 3000 Leuven, Belgium; Laboratory for Biological Psychology, KU Leuven, 3000 Leuven, Belgium.
  • D'Hooge R; KU Leuven, Leuven Brain Institute, 3000 Leuven, Belgium; Laboratory for Biological Psychology, KU Leuven, 3000 Leuven, Belgium.
  • Thal DR; KU Leuven, Leuven Brain Institute, 3000 Leuven, Belgium; Laboratory for Neuropathology, KU Leuven, and Department of Pathology, UZ Leuven, 3000 Leuven, Belgium.
  • Zetterberg H; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, 431 80 Mölndal, Sweden; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, WC1N 3BG, UK; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, Sahlgrenska Academy at the Un
  • Thuret S; Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 9RX, UK.
  • Fiers M; VIB Center for Brain & Disease Research, 3000 Leuven, Belgium; KU Leuven, Leuven Brain Institute, 3000 Leuven, Belgium.
  • Frigerio CS; UK Dementia Research Institute at UCL, London, WC1E 6BT, UK.
  • De Strooper B; VIB Center for Brain & Disease Research, 3000 Leuven, Belgium; KU Leuven, Leuven Brain Institute, 3000 Leuven, Belgium; UK Dementia Research Institute at UCL, London, WC1E 6BT, UK. Electronic address: b.strooper@ukdri.ucl.ac.uk.
  • Salta E; Laboratory of Neurogenesis and Neurodegeneration, Netherlands Institute for Neuroscience, 1105BA Amsterdam, the Netherlands. Electronic address: e.salta@nin.knaw.nl.
Cell Stem Cell ; 28(10): 1805-1821.e8, 2021 10 07.
Article em En | MEDLINE | ID: mdl-34033742
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Doença de Alzheimer Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cell Stem Cell Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Bélgica
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Doença de Alzheimer Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cell Stem Cell Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Bélgica