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Cross-platform validation of neurotransmitter release impairments in schizophrenia patient-derived NRXN1-mutant neurons.
Pak, ChangHui; Danko, Tamas; Mirabella, Vincent R; Wang, Jinzhao; Liu, Yingfei; Vangipuram, Madhuri; Grieder, Sarah; Zhang, Xianglong; Ward, Thomas; Huang, Yu-Wen Alvin; Jin, Kang; Dexheimer, Philip; Bardes, Eric; Mitelpunkt, Alexis; Ma, Junyi; McLachlan, Michael; Moore, Jennifer C; Qu, Pingping; Purmann, Carolin; Dage, Jeffrey L; Swanson, Bradley J; Urban, Alexander E; Aronow, Bruce J; Pang, Zhiping P; Levinson, Douglas F; Wernig, Marius; Südhof, Thomas C.
Afiliação
  • Pak C; Department of Molecular & Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305; cpak@umass.edu tcs1@stanford.edu.
  • Danko T; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305.
  • Mirabella VR; Department of Biochemistry & Molecular Biology, University of Massachusetts, Amherst, MA 01003.
  • Wang J; Department of Molecular & Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305.
  • Liu Y; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305.
  • Vangipuram M; Child Health Institute of New Jersey, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08901.
  • Grieder S; Department of Neuroscience and Cell Biology, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08901.
  • Zhang X; Department of Molecular & Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305.
  • Ward T; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305.
  • Huang YA; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305.
  • Jin K; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305.
  • Dexheimer P; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305.
  • Bardes E; Department of Psychiatry & Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305.
  • Mitelpunkt A; Department of Psychiatry & Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305.
  • Ma J; Department of Molecular & Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305.
  • McLachlan M; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305.
  • Moore JC; Department of Biomedical Informatics, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.
  • Qu P; Department of Pediatrics, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.
  • Purmann C; Department of Biomedical Informatics, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.
  • Dage JL; Department of Pediatrics, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.
  • Swanson BJ; Department of Biomedical Informatics, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.
  • Urban AE; Department of Pediatrics, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.
  • Aronow BJ; Department of Biomedical Informatics, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.
  • Pang ZP; Department of Pediatrics, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.
  • Levinson DF; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel 6997801.
  • Wernig M; Fujifilm Cellular Dynamics, Inc., Madison, WI 53711.
  • Südhof TC; Fujifilm Cellular Dynamics, Inc., Madison, WI 53711.
Proc Natl Acad Sci U S A ; 118(22)2021 06 01.
Article em En | MEDLINE | ID: mdl-34035170
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esquizofrenia / Proteínas de Ligação ao Cálcio / Neurotransmissores / Moléculas de Adesão de Célula Nervosa / Mutação / Neurônios Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esquizofrenia / Proteínas de Ligação ao Cálcio / Neurotransmissores / Moléculas de Adesão de Célula Nervosa / Mutação / Neurônios Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2021 Tipo de documento: Article