Label-Free Multimodal Multiphoton Intravital Imaging.
Adv Exp Med Biol
; 3233: 127-146, 2021.
Article
em En
| MEDLINE
| ID: mdl-34053026
ABSTRACT
Label-free intravital optical imaging is an emergent visualization tool that is not only useful for basic biological research, but also for preclinical research with potential translational clinical applications. The complete absence of exogenous labeling or genetic alterations avoids plausible harmful perturbation to biological processes and the pristine physiological environment, as the endogenous biomolecules enable intrinsic imaging contrasts to interrogate various live multicellular organisms of interest. This tool has evolved from single-modality, single-photon imaging into multimodal multiphoton imaging, in order to gain different contrasts simultaneously during imaging sessions, and permit long-term time-lapse studies that have begun to spawn more diverse applications.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Diagnóstico por Imagem
/
Microscopia Intravital
Tipo de estudo:
Diagnostic_studies
Idioma:
En
Revista:
Adv Exp Med Biol
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Estados Unidos