Iprodione and/or chlorpyrifos exposure induced testicular toxicity in adult rats by suppression of steroidogenic genes and SIRT1/TERT/PGC-1&#945; pathway.

Abd-Elhakim, Yasmina M; El Sharkawy, Nabela I; El Bohy, Khlood M; Hassan, Mona A; Gharib, Heba S A; El-Metwally, Abeer E; Arisha, Ahmed Hamed; Imam, Tamer S

Iprodione and/or chlorpyrifos exposure induced testicular toxicity in adult rats by suppression of steroidogenic genes and SIRT1/TERT/PGC-1α pathway.

Abd-Elhakim, Yasmina M; El Sharkawy, Nabela I; El Bohy, Khlood M; Hassan, Mona A; Gharib, Heba S A; El-Metwally, Abeer E; Arisha, Ahmed Hamed; Imam, Tamer S.

Afiliação

Abd-Elhakim YM; Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.
El Sharkawy NI; Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.
El Bohy KM; Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.
Hassan MA; Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt. monaabdelhady91@yahoo.com.
Gharib HSA; Department of Veterinary Public Health, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.
El-Metwally AE; Department of Pathology, Animal Reproduction Research Institute, Giza, Egypt.
Arisha AH; Department of Animal Physiology and Biochemistry, Faculty of Veterinary Medicine, Badr University in Cairo (BUC), Badr City, Cairo, Egypt.
Imam TS; Department of Physiology, Faculty of Veterinary Medicine, Zagazig University, Sharkia, Zagazig, Egypt.

Environ Sci Pollut Res Int ; 28(40): 56491-56506, 2021 Oct.

Article em En | MEDLINE | ID: mdl-34060014

Assuntos

Clorpirifos; Aminoimidazol Carboxamida/análogos & derivados; Animais; Clorpirifos/metabolismo; Clorpirifos/toxicidade; Hidantoínas; Masculino; Estresse Oxidativo; Coativador 1-alfa do Receptor gama Ativado por Proliferador de Peroxissomo/genética; Ratos; Sirtuína 1/metabolismo; Testículo/metabolismo

Palavras-chave

Chlorpyrifos; Iprodione; Male reproductive toxicity; Sexual behavior; Steroidogenic genes, SIRT1/TERT/PGC-1α pathway

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Clorpirifos Limite: Animals Idioma: En Revista: Environ Sci Pollut Res Int Assunto da revista: SAUDE AMBIENTAL / TOXICOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Egito

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