Human vitamin B-6 pools estimated through muscle biopsies.
Am J Clin Nutr
; 48(2): 291-4, 1988 Aug.
Article
em En
| MEDLINE
| ID: mdl-3407607
ABSTRACT
Previous estimates of total vitamin B-6 pools in humans based on extrapolations from tracer studies yielded values of 107-190 mumol when the tracer was administered orally and 345-725 mumol when the tracer was administered intravenously. To obtain a more direct estimate of vitamin B-6 pools, muscle biopsies from five female and seven male adults were analyzed by cation-exchange chromatography. Total muscle mass was estimated from creatinine excretion and the assumption that muscle is 40% of the body weight. The total muscle vitamin B-6 pool was estimated to be 917 +/- 319 mumol in the females and 850 +/- 216 mumol in the males. Because muscle accounts for approximately 80% of the vitamin B-6 in the body, the total body pool of vitamin B-6 in adult humans is probably approximately 1000 mumol.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Piridoxina
/
Músculos
Limite:
Adult
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Am J Clin Nutr
Ano de publicação:
1988
Tipo de documento:
Article