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TP53 missense mutations in PDAC are associated with enhanced fibrosis and an immunosuppressive microenvironment.
Maddalena, Martino; Mallel, Giuseppe; Nataraj, Nishanth Belugali; Shreberk-Shaked, Michal; Hassin, Ori; Mukherjee, Saptaparna; Arandkar, Sharathchandra; Rotkopf, Ron; Kapsack, Abby; Lambiase, Giuseppina; Pellegrino, Bianca; Ben-Isaac, Eyal; Golani, Ofra; Addadi, Yoseph; Hajaj, Emma; Eilam, Raya; Straussman, Ravid; Yarden, Yosef; Lotem, Michal; Oren, Moshe.
Afiliação
  • Maddalena M; Department of Molecular Cell Biology, Weizmann Institute of Science, 76100 Rehovot, Israel.
  • Mallel G; Department of Molecular Cell Biology, Weizmann Institute of Science, 76100 Rehovot, Israel.
  • Nataraj NB; Department of Biological Regulation, Weizmann Institute of Science, 76100 Rehovot, Israel.
  • Shreberk-Shaked M; Department of Molecular Cell Biology, Weizmann Institute of Science, 76100 Rehovot, Israel.
  • Hassin O; Department of Molecular Cell Biology, Weizmann Institute of Science, 76100 Rehovot, Israel.
  • Mukherjee S; Department of Molecular Cell Biology, Weizmann Institute of Science, 76100 Rehovot, Israel.
  • Arandkar S; Department of Molecular Cell Biology, Weizmann Institute of Science, 76100 Rehovot, Israel.
  • Rotkopf R; Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, 410210 Kharghar, India.
  • Kapsack A; Department of Life Sciences Core Facilities, Faculty of Biochemistry, Weizmann Institute of Science, 76100 Rehovot, Israel.
  • Lambiase G; Department of Molecular Cell Biology, Weizmann Institute of Science, 76100 Rehovot, Israel.
  • Pellegrino B; Department of Molecular Cell Biology, Weizmann Institute of Science, 76100 Rehovot, Israel.
  • Ben-Isaac E; Department of Molecular Cell Biology, Weizmann Institute of Science, 76100 Rehovot, Israel.
  • Golani O; Department of Life Sciences Core Facilities, Faculty of Biochemistry, Weizmann Institute of Science, 76100 Rehovot, Israel.
  • Addadi Y; Department of Life Sciences Core Facilities, Faculty of Biochemistry, Weizmann Institute of Science, 76100 Rehovot, Israel.
  • Hajaj E; Department of Life Sciences Core Facilities, Faculty of Biochemistry, Weizmann Institute of Science, 76100 Rehovot, Israel.
  • Eilam R; Sharett Institute of Oncology, Hadassah Hebrew University Hospital, 91120 Jerusalem, Israel.
  • Straussman R; Department of Veterinary Resources, Weizmann Institute of Science, 76100 Rehovot, Israel.
  • Yarden Y; Department of Molecular Cell Biology, Weizmann Institute of Science, 76100 Rehovot, Israel.
  • Lotem M; Department of Biological Regulation, Weizmann Institute of Science, 76100 Rehovot, Israel.
  • Oren M; Sharett Institute of Oncology, Hadassah Hebrew University Hospital, 91120 Jerusalem, Israel.
Proc Natl Acad Sci U S A ; 118(23)2021 06 08.
Article em En | MEDLINE | ID: mdl-34088837
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Fibrose / Proteína Supressora de Tumor p53 / Mutação de Sentido Incorreto / Carcinoma Ductal Pancreático Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Israel
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Fibrose / Proteína Supressora de Tumor p53 / Mutação de Sentido Incorreto / Carcinoma Ductal Pancreático Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Israel