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A Crohn's Disease-associated IL2RA Enhancer Variant Determines the Balance of T Cell Immunity by Regulating Responsiveness to IL-2 Signalling.
Goldberg, Rimma; Clough, Jennie N; Roberts, Luke B; Sanchez, Jenifer; Kordasti, Shahram; Petrov, Nedyalko; Hertweck, Arnulf; Lorenc, Anna; Jackson, Ian; Tasker, Scott; Appios, Anna; Omer, Omer; Parkes, Miles; Prescott, Natalie; Jenner, Richard G; Irving, Peter M; Lord, Graham M.
Afiliação
  • Goldberg R; School of Immunology and Microbial Sciences, King's College London, London, UK.
  • Clough JN; School of Clinical Sciences, Monash University, Melbourne, VIC, Australia.
  • Roberts LB; Department of Gastroenterology, Monash Health, Melbourne, VIC, Australia.
  • Sanchez J; School of Immunology and Microbial Sciences, King's College London, London, UK.
  • Kordasti S; IBD Unit, Gastroenterology Department, Guy's and St Thomas' NHS Trust, London, UK.
  • Petrov N; National Institute for Health Research Biomedical Research Centre, Guy's and St Thomas' NHS Trust and King's College London, London, UK.
  • Hertweck A; School of Immunology and Microbial Sciences, King's College London, London, UK.
  • Lorenc A; National Institute for Health Research Biomedical Research Centre, Guy's and St Thomas' NHS Trust and King's College London, London, UK.
  • Jackson I; School of Immunology and Microbial Sciences, King's College London, London, UK.
  • Tasker S; CRUK-KHP Cancer Centre, School of Cancer and Pharmaceutical Sciences, King's College London, London, UK.
  • Appios A; National Institute for Health Research Biomedical Research Centre, Guy's and St Thomas' NHS Trust and King's College London, London, UK.
  • Omer O; UCL Cancer Institute, University College London, London, UK.
  • Parkes M; School of Immunology and Microbial Sciences, King's College London, London, UK.
  • Prescott N; School of Immunology and Microbial Sciences, King's College London, London, UK.
  • Jenner RG; National Institute for Health Research Biomedical Research Centre, Guy's and St Thomas' NHS Trust and King's College London, London, UK.
  • Irving PM; School of Immunology and Microbial Sciences, King's College London, London, UK.
  • Lord GM; School of Immunology and Microbial Sciences, King's College London, London, UK.
J Crohns Colitis ; 15(12): 2054-2065, 2021 Dec 18.
Article em En | MEDLINE | ID: mdl-34120187
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T CD4-Positivos / Doença de Crohn / Interleucina-2 / Linfócitos T Reguladores / Subunidade alfa de Receptor de Interleucina-2 Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: J Crohns Colitis Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T CD4-Positivos / Doença de Crohn / Interleucina-2 / Linfócitos T Reguladores / Subunidade alfa de Receptor de Interleucina-2 Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: J Crohns Colitis Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido