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Next-generation Bruton's tyrosine kinase inhibitor BIIB091 selectively and potently inhibits B cell and Fc receptor signaling and downstream functions in B cells and myeloid cells.
Bame, Eris; Tang, Hao; Burns, Jeremy C; Arefayene, Million; Michelsen, Klaus; Ma, Bin; Marx, Isaac; Prince, Robin; Roach, Allie M; Poreci, Urjana; Donaldson, Douglas; Cullen, Patrick; Casey, Fergal; Zhu, Jing; Carlile, Thomas M; Sangurdekar, Dipen; Zhang, Baohong; Trapa, Patrick; Santoro, Joseph; Muragan, Param; Pellerin, Alex; Rubino, Stephen; Gianni, Davide; Bajrami, Bekim; Peng, Xiaomei; Coppell, Alex; Riester, Katherine; Belachew, Shibeshih; Mehta, Devangi; Palte, Mike; Hopkins, Brian T; Scaramozza, Matthew; Franchimont, Nathalie; Mingueneau, Michael.
Afiliação
  • Bame E; Clinical Sciences Biogen Cambridge MA USA.
  • Tang H; Biogen Research Biogen Cambridge MA USA.
  • Burns JC; Biogen Research Biogen Cambridge MA USA.
  • Arefayene M; Clinical Sciences Biogen Cambridge MA USA.
  • Michelsen K; Biotherapeutics and Medicinal Sciences Biogen Cambridge MA USA.
  • Ma B; Present address: Relay Therapeutics Cambridge MA USA.
  • Marx I; Biotherapeutics and Medicinal Sciences Biogen Cambridge MA USA.
  • Prince R; Biotherapeutics and Medicinal Sciences Biogen Cambridge MA USA.
  • Roach AM; Biotherapeutics and Medicinal Sciences Biogen Cambridge MA USA.
  • Poreci U; Biogen Research Biogen Cambridge MA USA.
  • Donaldson D; Present address: Gilead Sciences Seattle WA USA.
  • Cullen P; Clinical Sciences Biogen Cambridge MA USA.
  • Casey F; Present address: Pandion Therapeutics Watertown MA USA.
  • Zhu J; Clinical Sciences Biogen Cambridge MA USA.
  • Carlile TM; Present address: Giner Labs Newton MA USA.
  • Sangurdekar D; Biogen Research Biogen Cambridge MA USA.
  • Zhang B; Biogen Research Biogen Cambridge MA USA.
  • Trapa P; Biogen Research Biogen Cambridge MA USA.
  • Santoro J; Biogen Research Biogen Cambridge MA USA.
  • Muragan P; Biogen Research Biogen Cambridge MA USA.
  • Pellerin A; Present address: Takeda Cambridge MA USA.
  • Rubino S; Biogen Research Biogen Cambridge MA USA.
  • Gianni D; Biotherapeutics and Medicinal Sciences Biogen Cambridge MA USA.
  • Bajrami B; Biotherapeutics and Medicinal Sciences Biogen Cambridge MA USA.
  • Peng X; Biotherapeutics and Medicinal Sciences Biogen Cambridge MA USA.
  • Coppell A; Biogen Research Biogen Cambridge MA USA.
  • Riester K; Biogen Research Biogen Cambridge MA USA.
  • Belachew S; Biotherapeutics and Medicinal Sciences Biogen Cambridge MA USA.
  • Mehta D; Biotherapeutics and Medicinal Sciences Biogen Cambridge MA USA.
  • Palte M; Global Safety and Regulatory Sciences Biogen Cambridge MA USA.
  • Hopkins BT; Clinical Operations Biogen Maidenhead UK.
  • Scaramozza M; Clinical Sciences Biogen Cambridge MA USA.
  • Franchimont N; Personalized Health Research Biogen Baar Switzerland.
  • Mingueneau M; Clinical Sciences Biogen Cambridge MA USA.
Clin Transl Immunology ; 10(6): e1295, 2021.
Article em En | MEDLINE | ID: mdl-34141433
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Clin Transl Immunology Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Clin Transl Immunology Ano de publicação: 2021 Tipo de documento: Article