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A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage.
Zou, Xueqing; Koh, Gene Ching Chiek; Nanda, Arjun Scott; Degasperi, Andrea; Urgo, Katie; Roumeliotis, Theodoros I; Agu, Chukwuma A; Badja, Cherif; Momen, Sophie; Young, Jamie; Amarante, Tauanne Dias; Side, Lucy; Brice, Glen; Perez-Alonso, Vanesa; Rueda, Daniel; Gomez, Celine; Bushell, Wendy; Harris, Rebecca; Choudhary, Jyoti S; Jiricny, Josef; Skarnes, William C; Nik-Zainal, Serena.
Afiliação
  • Zou X; Academic Department of Medical Genetics, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
  • Koh GCC; MRC Cancer Unit, University of Cambridge, Cambridge, UK.
  • Nanda AS; Wellcome Sanger Institute, Hinxton, UK.
  • Degasperi A; Academic Department of Medical Genetics, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
  • Urgo K; MRC Cancer Unit, University of Cambridge, Cambridge, UK.
  • Roumeliotis TI; Wellcome Sanger Institute, Hinxton, UK.
  • Agu CA; Academic Department of Medical Genetics, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
  • Badja C; MRC Cancer Unit, University of Cambridge, Cambridge, UK.
  • Momen S; Academic Department of Medical Genetics, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
  • Young J; MRC Cancer Unit, University of Cambridge, Cambridge, UK.
  • Amarante TD; Wellcome Sanger Institute, Hinxton, UK.
  • Side L; Wellcome Sanger Institute, Hinxton, UK.
  • Brice G; The Institute of Cancer Research, Chester Beatty Laboratories, London, UK.
  • Perez-Alonso V; Wellcome Sanger Institute, Hinxton, UK.
  • Rueda D; Academic Department of Medical Genetics, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
  • Gomez C; MRC Cancer Unit, University of Cambridge, Cambridge, UK.
  • Bushell W; Wellcome Sanger Institute, Hinxton, UK.
  • Harris R; Academic Department of Medical Genetics, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
  • Choudhary JS; MRC Cancer Unit, University of Cambridge, Cambridge, UK.
  • Jiricny J; Academic Department of Medical Genetics, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
  • Skarnes WC; MRC Cancer Unit, University of Cambridge, Cambridge, UK.
  • Nik-Zainal S; UCL Institute for Women's Health, Great Ormond Street Hospital, London, UK.
Nat Cancer ; 2(6): 643-657, 2021 06.
Article em En | MEDLINE | ID: mdl-34164627
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Células-Tronco Pluripotentes Induzidas Limite: Humans Idioma: En Revista: Nat Cancer Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Células-Tronco Pluripotentes Induzidas Limite: Humans Idioma: En Revista: Nat Cancer Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido