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Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons.
Steg, Leonard C; Shireby, Gemma L; Imm, Jennifer; Davies, Jonathan P; Franklin, Alice; Flynn, Robert; Namboori, Seema C; Bhinge, Akshay; Jeffries, Aaron R; Burrage, Joe; Neilson, Grant W A; Walker, Emma M; Perfect, Leo W; Price, Jack; McAlonan, Grainne; Srivastava, Deepak P; Bray, Nicholas J; Cope, Emma L; Jones, Kimberley M; Allen, Nicholas D; Pishva, Ehsan; Dempster, Emma L; Lunnon, Katie; Mill, Jonathan; Hannon, Eilis.
Afiliação
  • Steg LC; College of Medicine and Health, University of Exeter, RILD Building Level 3, Barrack Rd, Exeter, UK.
  • Shireby GL; College of Medicine and Health, University of Exeter, RILD Building Level 3, Barrack Rd, Exeter, UK.
  • Imm J; College of Medicine and Health, University of Exeter, RILD Building Level 3, Barrack Rd, Exeter, UK.
  • Davies JP; College of Medicine and Health, University of Exeter, RILD Building Level 3, Barrack Rd, Exeter, UK.
  • Franklin A; College of Medicine and Health, University of Exeter, RILD Building Level 3, Barrack Rd, Exeter, UK.
  • Flynn R; College of Medicine and Health, University of Exeter, RILD Building Level 3, Barrack Rd, Exeter, UK.
  • Namboori SC; College of Medicine and Health, University of Exeter, RILD Building Level 3, Barrack Rd, Exeter, UK.
  • Bhinge A; College of Medicine and Health, University of Exeter, RILD Building Level 3, Barrack Rd, Exeter, UK.
  • Jeffries AR; College of Medicine and Health, University of Exeter, RILD Building Level 3, Barrack Rd, Exeter, UK.
  • Burrage J; College of Medicine and Health, University of Exeter, RILD Building Level 3, Barrack Rd, Exeter, UK.
  • Neilson GWA; College of Medicine and Health, University of Exeter, RILD Building Level 3, Barrack Rd, Exeter, UK.
  • Walker EM; College of Medicine and Health, University of Exeter, RILD Building Level 3, Barrack Rd, Exeter, UK.
  • Perfect LW; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
  • Price J; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
  • McAlonan G; Department of Forensic and Neurodevelopmental Sciences, King's College London, London, UK.
  • Srivastava DP; MRC Centre for Neurodevelopmental Disorders, King's College London, London, UK.
  • Bray NJ; Behavioural and Developmental Psychiatry, South London and Maudsley NHS Foundation Trust, London, UK.
  • Cope EL; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
  • Jones KM; MRC Centre for Neurodevelopmental Disorders, King's College London, London, UK.
  • Allen ND; Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK.
  • Pishva E; School of Biosciences, Cardiff University, Cardiff, UK.
  • Dempster EL; School of Biosciences, Cardiff University, Cardiff, UK.
  • Lunnon K; School of Biosciences, Cardiff University, Cardiff, UK.
  • Mill J; College of Medicine and Health, University of Exeter, RILD Building Level 3, Barrack Rd, Exeter, UK.
  • Hannon E; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht, The Netherlands.
Mol Brain ; 14(1): 98, 2021 06 26.
Article em En | MEDLINE | ID: mdl-34174924

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Relógios Biológicos / Encéfalo / Senescência Celular / Epigênese Genética / Células-Tronco Pluripotentes Induzidas / Feto / Modelos Biológicos / Neurônios Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Pregnancy Idioma: En Revista: Mol Brain Assunto da revista: BIOLOGIA MOLECULAR / CEREBRO Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Relógios Biológicos / Encéfalo / Senescência Celular / Epigênese Genética / Células-Tronco Pluripotentes Induzidas / Feto / Modelos Biológicos / Neurônios Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Pregnancy Idioma: En Revista: Mol Brain Assunto da revista: BIOLOGIA MOLECULAR / CEREBRO Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido