Antimicrobial immunotherapeutics: past, present and future.
Emerg Top Life Sci
; 5(5): 609-628, 2021 11 12.
Article
em En
| MEDLINE
| ID: mdl-34196722
ABSTRACT
In this age of antimicrobial resistance (AMR) there is an urgent need for novel antimicrobials. One area of recent interest is in developing antimicrobial effector molecules, and even cell-based therapies, based on those of the immune system. In this review, some of the more interesting approaches will be discussed, including immune checkpoint inhibitors, Interferons (IFNs), Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF), Chimeric Antigen Receptor (CAR) T cells, Antibodies, Vaccines and the potential role of trained immunity in protection from and/or treatment of infection.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Imunoterapia
/
Anti-Infecciosos
Idioma:
En
Revista:
Emerg Top Life Sci
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Reino Unido