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Ethics and regulatory considerations for the clinical translation of somatic cell human epigenetic editing.
Zeps, Nikolajs; Lysaght, Tamra; Chadwick, Ruth; Erler, Alexandre; Foo, Roger; Giordano, Simona; San Lai, Poh; Schaefer, G Owen; Xafis, Vicki; Chew, Wei Leong; Sugarman, Jeremy.
Afiliação
  • Zeps N; Eastern Health Clinical School, Monash University, Melbourne, VIC, Australia.
  • Lysaght T; Centre for Biomedical Ethics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. Electronic address: tlysaght@nus.edu.sg.
  • Chadwick R; School of Social Sciences, Cardiff University, Cardiff, UK.
  • Erler A; CUHK Centre for Bioethics, Chinese University of Hong Kong, Hong Kong, China; Philosophy Department, Chinese University of Hong Kong, Hong Kong, China.
  • Foo R; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.
  • Giordano S; School of Law, University of Manchester, Manchester, UK.
  • San Lai P; Department of Paediatrics, National University of Singapore, Singapore, Singapore.
  • Schaefer GO; Centre for Biomedical Ethics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Xafis V; Centre for Biomedical Ethics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Chew WL; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.
  • Sugarman J; Berman Institute of Bioethics, Johns Hopkins University, Baltimore, MA, USA.
Stem Cell Reports ; 16(7): 1652-1655, 2021 07 13.
Article em En | MEDLINE | ID: mdl-34214486
Altering the human epigenome with gene-editing technology in attempt to treat a variety of diseases and conditions seems scientifically feasible. We explore some of the ethical and regulatory issues related to the clinical translation of human epigenetic editing arguing that such approaches should be considered akin to somatic therapies.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pesquisa Translacional Biomédica / Epigenômica / Edição de Genes Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Stem Cell Reports Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Austrália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pesquisa Translacional Biomédica / Epigenômica / Edição de Genes Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Stem Cell Reports Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Austrália