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Drug-like sphingolipid SH-BC-893 opposes ceramide-induced mitochondrial fission and corrects diet-induced obesity.
Jayashankar, Vaishali; Selwan, Elizabeth; Hancock, Sarah E; Verlande, Amandine; Goodson, Maggie O; Eckenstein, Kazumi H; Milinkeviciute, Giedre; Hoover, Brianna M; Chen, Bin; Fleischman, Angela G; Cramer, Karina S; Hanessian, Stephen; Masri, Selma; Turner, Nigel; Edinger, Aimee L.
Afiliação
  • Jayashankar V; Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA, USA.
  • Selwan E; Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA, USA.
  • Hancock SE; School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.
  • Verlande A; Department of Biological Chemistry, University of California Irvine, Irvine, CA, USA.
  • Goodson MO; Department of Biological Chemistry, University of California Irvine, Irvine, CA, USA.
  • Eckenstein KH; Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA, USA.
  • Milinkeviciute G; Department of Neurobiology and Behavior, University of California Irvine, Irvine, CA, USA.
  • Hoover BM; Division of Hematology/Oncology, Department of Medicine, University of California, Irvine, CA, USA.
  • Chen B; Department of Chemistry, Université de Montréal, Montréal, QC, Canada.
  • Fleischman AG; Division of Hematology/Oncology, Department of Medicine, University of California, Irvine, CA, USA.
  • Cramer KS; Department of Neurobiology and Behavior, University of California Irvine, Irvine, CA, USA.
  • Hanessian S; Department of Chemistry, Université de Montréal, Montréal, QC, Canada.
  • Masri S; Department of Biological Chemistry, University of California Irvine, Irvine, CA, USA.
  • Turner N; School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.
  • Edinger AL; Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA, USA.
EMBO Mol Med ; 13(8): e13086, 2021 08 09.
Article em En | MEDLINE | ID: mdl-34231322
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esfingolipídeos / Resistência à Insulina / Dinâmica Mitocondrial / Obesidade Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: EMBO Mol Med Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esfingolipídeos / Resistência à Insulina / Dinâmica Mitocondrial / Obesidade Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: EMBO Mol Med Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos