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Cell competition acts as a purifying selection to eliminate cells with mitochondrial defects during early mouse development.
Lima, Ana; Lubatti, Gabriele; Burgstaller, Jörg; Hu, Di; Green, Alistair P; Di Gregorio, Aida; Zawadzki, Tamzin; Pernaute, Barbara; Mahammadov, Elmir; Perez-Montero, Salvador; Dore, Marian; Sanchez, Juan Miguel; Bowling, Sarah; Sancho, Margarida; Kolbe, Thomas; Karimi, Mohammad M; Carling, David; Jones, Nick; Srinivas, Shankar; Scialdone, Antonio; Rodriguez, Tristan A.
Afiliação
  • Lima A; National Heart and Lung Institute, Imperial College London, London, UK.
  • Lubatti G; MRC London Institute of Medical Sciences (LMS), Institute of Clinical Sciences, Imperial College London, London, UK.
  • Burgstaller J; Institute of Epigenetics and Stem Cells, Helmholtz Zentrum München, Munich, Germany.
  • Hu D; Institute of Functional Epigenetics, Helmholtz Zentrum München, Neuherberg, Germany.
  • Green AP; Institute of Computational Biology, Helmholtz Zentrum München, Neuherberg, Germany.
  • Di Gregorio A; Institute of Animal Breeding and Genetics, University of Veterinary Medicine, Vienna, Austria.
  • Zawadzki T; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
  • Pernaute B; EPSRC Centre for the Mathematics of Precision Healthcare, Department of Mathematics, Imperial College London, London, UK.
  • Mahammadov E; National Heart and Lung Institute, Imperial College London, London, UK.
  • Perez-Montero S; National Heart and Lung Institute, Imperial College London, London, UK.
  • Dore M; National Heart and Lung Institute, Imperial College London, London, UK.
  • Sanchez JM; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
  • Bowling S; Institute of Epigenetics and Stem Cells, Helmholtz Zentrum München, Munich, Germany.
  • Sancho M; Institute of Functional Epigenetics, Helmholtz Zentrum München, Neuherberg, Germany.
  • Kolbe T; Institute of Computational Biology, Helmholtz Zentrum München, Neuherberg, Germany.
  • Karimi MM; National Heart and Lung Institute, Imperial College London, London, UK.
  • Carling D; MRC London Institute of Medical Sciences (LMS), Institute of Clinical Sciences, Imperial College London, London, UK.
  • Jones N; National Heart and Lung Institute, Imperial College London, London, UK.
  • Srinivas S; Orchard Therapeutics, London, UK.
  • Scialdone A; National Heart and Lung Institute, Imperial College London, London, UK.
  • Rodriguez TA; National Heart and Lung Institute, Imperial College London, London, UK.
Nat Metab ; 3(8): 1091-1108, 2021 08.
Article em En | MEDLINE | ID: mdl-34253906

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenvolvimento Embrionário / Embrião de Mamíferos / Competição entre as Células / Mitocôndrias Limite: Animals Idioma: En Revista: Nat Metab Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenvolvimento Embrionário / Embrião de Mamíferos / Competição entre as Células / Mitocôndrias Limite: Animals Idioma: En Revista: Nat Metab Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido