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FRET-Based Screening Identifies p38 MAPK and PKC Inhibition as Targets for Prevention of Seeded α-Synuclein Aggregation.
Svanbergsson, Alexander; Ek, Fredrik; Martinsson, Isak; Rodo, Jordi; Liu, Di; Brandi, Edoardo; Haikal, Caroline; Torres-Garcia, Laura; Li, Wen; Gouras, Gunnar; Olsson, Roger; Björklund, Tomas; Li, Jia-Yi.
Afiliação
  • Svanbergsson A; Department of Experimental Medicine, Neural Plasticity and Repair, Lund University, Lund, Sweden.
  • Ek F; Chemical Biology & Therapeutics, Department of Experimental Medicinal Science, Lund University, Lund, Sweden.
  • Martinsson I; Experimental Dementia Research, Department of Experimental Medicine, Lund University, Lund, Sweden.
  • Rodo J; Department of Experimental Medicine, Neural Plasticity and Repair, Lund University, Lund, Sweden.
  • Liu D; Department of Experimental Medicine, Neural Plasticity and Repair, Lund University, Lund, Sweden.
  • Brandi E; Department of Experimental Medicine, Neural Plasticity and Repair, Lund University, Lund, Sweden.
  • Haikal C; Department of Experimental Medicine, Neural Plasticity and Repair, Lund University, Lund, Sweden.
  • Torres-Garcia L; Department of Experimental Medicine, Neural Plasticity and Repair, Lund University, Lund, Sweden.
  • Li W; Experimental Dementia Research, Department of Experimental Medicine, Lund University, Lund, Sweden.
  • Gouras G; Department of Experimental Medicine, Neural Plasticity and Repair, Lund University, Lund, Sweden.
  • Olsson R; Experimental Dementia Research, Department of Experimental Medicine, Lund University, Lund, Sweden.
  • Björklund T; Chemical Biology & Therapeutics, Department of Experimental Medicinal Science, Lund University, Lund, Sweden.
  • Li JY; Molecular Neuromodulation, Department of Experimental Medicine, Lund University, Lund, Sweden.
Neurotherapeutics ; 18(3): 1692-1709, 2021 07.
Article em En | MEDLINE | ID: mdl-34258749

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Quinase C / Transferência Ressonante de Energia de Fluorescência / Proteínas Quinases p38 Ativadas por Mitógeno / Inibidores Enzimáticos / Alfa-Sinucleína / Agregação Patológica de Proteínas Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Humans Idioma: En Revista: Neurotherapeutics Assunto da revista: NEUROLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Suécia

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Quinase C / Transferência Ressonante de Energia de Fluorescência / Proteínas Quinases p38 Ativadas por Mitógeno / Inibidores Enzimáticos / Alfa-Sinucleína / Agregação Patológica de Proteínas Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Humans Idioma: En Revista: Neurotherapeutics Assunto da revista: NEUROLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Suécia