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CKD-506: A novel HDAC6-selective inhibitor that exerts therapeutic effects in a rodent model of multiple sclerosis.
Bae, Daekwon; Lee, Ji-Young; Ha, Nina; Park, Jinsol; Baek, Jiyeon; Suh, Donghyeon; Lim, Hee Seon; Ko, Soo Min; Kim, Taehee; Som Jeong, Da; Son, Woo-Chan.
Afiliação
  • Bae D; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 05505, Republic of Korea. bdg088@ckdpharm.com.
  • Lee JY; Department of Pharmacology, CKD Research Institute, CKD Pharmaceutical Co, Yongin, 16995, Republic of Korea. bdg088@ckdpharm.com.
  • Ha N; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 05505, Republic of Korea.
  • Park J; Department of Pharmacology, CKD Research Institute, CKD Pharmaceutical Co, Yongin, 16995, Republic of Korea.
  • Baek J; Department of Pharmacology, CKD Research Institute, CKD Pharmaceutical Co, Yongin, 16995, Republic of Korea.
  • Suh D; Department of Pharmacology, CKD Research Institute, CKD Pharmaceutical Co, Yongin, 16995, Republic of Korea.
  • Lim HS; Department of Pharmacology, CKD Research Institute, CKD Pharmaceutical Co, Yongin, 16995, Republic of Korea.
  • Ko SM; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 05505, Republic of Korea.
  • Kim T; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 05505, Republic of Korea.
  • Som Jeong D; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 05505, Republic of Korea.
  • Son WC; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 05505, Republic of Korea.
Sci Rep ; 11(1): 14466, 2021 07 14.
Article em En | MEDLINE | ID: mdl-34262061
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encefalomielite Autoimune Experimental / Inibidores de Histona Desacetilases / Esclerose Múltipla Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encefalomielite Autoimune Experimental / Inibidores de Histona Desacetilases / Esclerose Múltipla Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article