A feasibility study of time of flight cone beam computed tomography imaging.
J Xray Sci Technol
; 29(5): 867-880, 2021.
Article
em En
| MEDLINE
| ID: mdl-34275923
ABSTRACT
BACKGROUND:
The time of flight (TOF) cone beam computed tomography (CBCT) was recently shown to reduce the X-ray scattering effects by 95% and improve the image CNR by 110% for large volume objects. The advancements in X-ray sources like in compact Free Electron Lasers (FEL) and advancements in detector technology show potential for the TOF method to be feasible in CBCT when imaging large objects.OBJECTIVE:
To investigate the feasibility and efficacy of TOF CBCT in imaging smaller objects with different targets such as bones and tumors embedded inside the background.METHODS:
The TOF method used in this work was verified using a 24 cm phantom. Then, the GATE software was used to simulate the CBCT imaging of an 8 cm diameter cylindrical water phantom with two bone targets using a modeled 20 keV quasi-energetic FEL source and various TOF resolutions ranging from 1 to 1000âps. An inhomogeneous breast phantom of similar size with tumor targets was also imaged using the same system setup.RESULTS:
The same results were obtained in the 24 cm phantom, which validated the applied CBCT simulation approach. For the case of 8 cm cylindrical phantom and bone target, a TOF resolution of 10âps improved the image contrast-to-noise ratio (CNR) by 57% and reduced the scatter-to-primary ratio (SPR) by 8.63. For the case of breast phantom and tumor target, image CNR was enhanced by 12% and SPR was reduced by 1.35 at 5âps temporal resolution.CONCLUSIONS:
This study indicates that a TOF resolution below 10âps is required to observe notable enhancements in the image quality and scatter reduction for small objects around 8 cm in diameter. The strong scattering targets such as bone can result in substantial improvements by using TOF CBCT.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tomografia Computadorizada de Feixe Cônico
Idioma:
En
Revista:
J Xray Sci Technol
Assunto da revista:
RADIOLOGIA
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Estados Unidos