Monomeric C-reactive protein promotes platelets to release mitochondrial DNA in anti-neutrophil cytoplasmic antibody-associated vasculitis.

Chen, Tong; Xu, Peng-Cheng; Gao, Shan; Hu, Shui-Yi; Wei, Li; Yan, Tie-Kun

Chen, Tong; Xu, Peng-Cheng; Gao, Shan; Hu, Shui-Yi; Wei, Li; Yan, Tie-Kun.

Afiliação

Chen T; Department of Hematology, Tianjin Medical University General Hospital, Tianjin, 300052, China. Electronic address: chentong2014601004@163.com.
Xu PC; Department of Nephrology, Tianjin Medical University General Hospital, Tianjin, 300052, China. Electronic address: nkxpc@163.com.
Gao S; Department of Nephrology, Tianjin Medical University General Hospital, Tianjin, 300052, China. Electronic address: leeshan1225@sina.com.
Hu SY; Department of Nephrology, Tianjin Medical University General Hospital, Tianjin, 300052, China. Electronic address: hushuiyi33@163.com.
Wei L; Department of Nephrology, Tianjin Medical University General Hospital, Tianjin, 300052, China. Electronic address: weilee1981@163.com.
Yan TK; Department of Nephrology, Tianjin Medical University General Hospital, Tianjin, 300052, China. Electronic address: tiekunyan@163.com.

Mol Immunol ; 137: 228-237, 2021 09.

Article em En | MEDLINE | ID: mdl-34293590

Assuntos

Vasculite Associada a Anticorpo Anticitoplasma de Neutrófilos/metabolismo; Anticorpos Anticitoplasma de Neutrófilos/metabolismo; Plaquetas/metabolismo; Proteína C-Reativa/metabolismo; DNA Mitocondrial/metabolismo; Idoso; Idoso de 80 Anos ou mais; Biomarcadores/metabolismo; Coagulação Sanguínea/fisiologia; Feminino; Humanos; Masculino; Microdomínios da Membrana/metabolismo; Pessoa de Meia-Idade; Neutrófilos/metabolismo; Ativação Plaquetária/fisiologia; Explosão Respiratória/fisiologia; Trombina/metabolismo

Palavras-chave

Antineutrophil cytoplasmic antibody-associated vasculitis; C-reactive protein; Mitochondrial DNA; Platelets

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plaquetas / Proteína C-Reativa / DNA Mitocondrial / Anticorpos Anticitoplasma de Neutrófilos / Vasculite Associada a Anticorpo Anticitoplasma de Neutrófilos Tipo de estudo: Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Mol Immunol Ano de publicação: 2021 Tipo de documento: Article

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