Genetic mapping of novel modifiers for Apc<sup>Min</sup> induced intestinal polyps' development using the genetic architecture power of the collaborative cross mice.

Dorman, Alexandra; Binenbaum, Ilona; Abu-Toamih Atamni, Hanifa J; Chatziioannou, Aristotelis; Tomlinson, Ian; Mott, Richard; Iraqi, Fuad A

Genetic mapping of novel modifiers for Apc^Min induced intestinal polyps' development using the genetic architecture power of the collaborative cross mice.

Dorman, Alexandra; Binenbaum, Ilona; Abu-Toamih Atamni, Hanifa J; Chatziioannou, Aristotelis; Tomlinson, Ian; Mott, Richard; Iraqi, Fuad A.

Afiliação

Dorman A; Department of Clinical Microbiology & Immunology, Sackler Faculty of Medicine, Ramat Aviv, 69978, Tel-Aviv, Israel.
Binenbaum I; Department of Biology, University of Patras, Patras, Greece.
Abu-Toamih Atamni HJ; Center of Systems Biology, Biomedical Research Foundation of the Academy of Athens, Athens, Greece.
Chatziioannou A; Department of Clinical Microbiology & Immunology, Sackler Faculty of Medicine, Ramat Aviv, 69978, Tel-Aviv, Israel.
Tomlinson I; Center of Systems Biology, Biomedical Research Foundation of the Academy of Athens, Athens, Greece.
Mott R; Cancer Research UK Edinburgh Centre, Charles and Ethel Barr Chair of Cancer Research, University of Edinburgh, Edinburgh, UK.
Iraqi FA; Department of Genetics, University Collage of London, London, UK.

BMC Genomics ; 22(1): 566, 2021 Jul 22.

Article em En | MEDLINE | ID: mdl-34294033

Assuntos

Polipose Adenomatosa do Colo; Camundongos de Cruzamento Colaborativo; Polipose Adenomatosa do Colo/genética; Animais; Feminino; Pólipos Intestinais/genética; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Locos de Características Quantitativas

Palavras-chave

Apc Min; Candidate genes; Collaborative cross; Colorectal cancer; Familial adenomatous polyposis; Genetic modifier; Moms; Phenotyping; QTL mapping; Recombinant inbred lines

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polipose Adenomatosa do Colo / Camundongos de Cruzamento Colaborativo Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: BMC Genomics Assunto da revista: GENETICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Israel

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