Anti-Inflammatory Effect of Very High Dose Local Vessel Wall Statin Administration: Poly(L,L-Lactide) Biodegradable Microspheres with Simvastatin for Drug Delivery System (DDS).

Wacinski, Piotr; Gadzinowski, Mariusz; Dabrowski, Wojciech; Szumilo, Justyna; Wacinski, Jakub; Oru, Nathalie; Vicaut, Eric; Czuczwar, Stanislaw; Kocki, Janusz; Basinska, Teresa; Slomkowski, Stanislaw

Wacinski, Piotr; Gadzinowski, Mariusz; Dabrowski, Wojciech; Szumilo, Justyna; Wacinski, Jakub; Oru, Nathalie; Vicaut, Eric; Czuczwar, Stanislaw; Kocki, Janusz; Basinska, Teresa; Slomkowski, Stanislaw.

Afiliação

Wacinski P; Department of Cardiology, Medical University of Lublin, Jaczewskiego 8, 20-950 Lublin, Poland.
Gadzinowski M; Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, H. Sienkiewicza 112, 90-363 Lodz, Poland.
Dabrowski W; Department of Anesthesiology, Medical University of Lublin, Jaczewskiego 8, 20-950 Lublin, Poland.
Szumilo J; Department of Pathology, Medical University of Lublin, Jaczewskiego 8b, 20-090 Lublin, Poland.
Wacinski J; Department of Cardiology, Medical University of Lublin, Jaczewskiego 8, 20-950 Lublin, Poland.
Oru N; Fernand Vidal Hospital, Universite de Médecine Paris 7, 75006 Paris, France.
Vicaut E; Fernand Vidal Hospital, Universite de Médecine Paris 7, 75006 Paris, France.
Czuczwar S; Department of Pathophysiology, Medical University of Lublin, Jaczewskiego 8b, 20-090 Lublin, Poland.
Kocki J; Department of Genetics, Medical University of Lublin, Radziwillowska 18, 20-080 Lublin, Poland.
Basinska T; Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, H. Sienkiewicza 112, 90-363 Lodz, Poland.
Slomkowski S; Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, H. Sienkiewicza 112, 90-363 Lodz, Poland.

Int J Mol Sci ; 22(14)2021 Jul 13.

Article em En | MEDLINE | ID: mdl-34299106

Assuntos

Anti-Inflamatórios/farmacologia; Anticolesterolemiantes/farmacologia; Dioxanos/química; Sistemas de Liberação de Medicamentos; Inflamação/tratamento farmacológico; Sinvastatina/farmacologia; Animais; Anti-Inflamatórios/química; Anticolesterolemiantes/administração & dosagem; Camundongos; Camundongos Endogâmicos BALB C; Microesferas; Ratos; Ratos Wistar; Sinvastatina/administração & dosagem

Palavras-chave

atherosclerosis; biodegradable microspheres; biomedical application; endothelium; inflammation; local drug delivery; poly(L,L-lactide) particles

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistemas de Liberação de Medicamentos / Sinvastatina / Dioxanos / Inflamação / Anti-Inflamatórios / Anticolesterolemiantes Limite: Animals Idioma: En Revista: Int J Mol Sci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Polônia

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