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Development of coumarin-thiosemicarbazone hybrids as aldose reductase inhibitors: Biological assays, molecular docking, simulation studies and ADME evaluation.
Imran, Aqeel; Tariq Shehzad, Muhammad; Al Adhami, Taha; Miraz Rahman, Khondaker; Hussain, Dilawar; Alharthy, Rima D; Shafiq, Zahid; Iqbal, Jamshed.
Afiliação
  • Imran A; Center for Advanced Drug Research, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan; Institute of Pharmaceutical Science, King's College London, 150 Stamford Street, London SE1 9NH, United Kingdom.
  • Tariq Shehzad M; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan 60800, Pakistan.
  • Al Adhami T; Institute of Pharmaceutical Science, King's College London, 150 Stamford Street, London SE1 9NH, United Kingdom.
  • Miraz Rahman K; Institute of Pharmaceutical Science, King's College London, 150 Stamford Street, London SE1 9NH, United Kingdom.
  • Hussain D; Center for Advanced Drug Research, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan.
  • Alharthy RD; Department of Chemistry, Science and Arts College, Rabigh Campus, King Abdulaziz University, Jeddah, Saudi Arabia.
  • Shafiq Z; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan 60800, Pakistan. Electronic address: zahidshafiq@bzu.edu.pk.
  • Iqbal J; Center for Advanced Drug Research, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan. Electronic address: drjamshed@cuiatd.edu.pk.
Bioorg Chem ; 115: 105164, 2021 10.
Article em En | MEDLINE | ID: mdl-34314916
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiossemicarbazonas / Aldeído Redutase / Cumarínicos / Inibidores Enzimáticos Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiossemicarbazonas / Aldeído Redutase / Cumarínicos / Inibidores Enzimáticos Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido