Your browser doesn't support javascript.
loading
De novo isolated myeloid sarcoma: comparative analysis of survival in 19 consecutive cases.
Begna, Kebede H; Kittur, Jaya; Yui, Jennifer; Gangat, Naseema; Patnaik, Mrinal M; Al-Kali, Aref; Elliott, Michelle A; Hogan, William J; Litzow, Mark R; Hook, Christopher C; Wolanskyj, Alexandra P; Howard, Matthew T; Hanson, Curtis A; Ketterling, Rhett P; Pardanani, Animesh D; Tefferi, Ayalew.
Afiliação
  • Begna KH; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Kittur J; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Yui J; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Gangat N; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Patnaik MM; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Al-Kali A; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Elliott MA; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Hogan WJ; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Litzow MR; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Hook CC; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Wolanskyj AP; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Howard MT; Division of Hematopathology, Mayo Clinic, Rochester, Minnesota, USA.
  • Hanson CA; Division of Hematopathology, Mayo Clinic, Rochester, Minnesota, USA.
  • Ketterling RP; Division of Cytogenetics, Department of Laboratory Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Pardanani AD; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Tefferi A; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Br J Haematol ; 195(3): 413-416, 2021 11.
Article em En | MEDLINE | ID: mdl-34346084
ABSTRACT
Institutional database search (1999-2020) for acute myeloid leukaemia (AML) identified 109 cases of myeloid sarcoma (MS), of which 19 were isolated and presented de novo. The latter displayed longer survival (median 78 months), compared to MS with synchronous intramedullary AML (n = 32; median 16 months) and de novo AML without MS (n = 729; median 22 months; P = 0·13). However, the difference in survival was no longer apparent after accounting for bone marrow cytogenetic risk status (P = 0·67). Treatment-induced MS tumour resolution was not affected by the presence of intramedullary disease (P = 0·61). The current study clarifies the prognosis of de novo isolated MS, in the context of AML.
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Segunda Neoplasia Primária / Sarcoma Mieloide Limite: Aged80 Idioma: En Revista: Br J Haematol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Segunda Neoplasia Primária / Sarcoma Mieloide Limite: Aged80 Idioma: En Revista: Br J Haematol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos