Your browser doesn't support javascript.
loading
Evidence from a meta-analysis for association of MC4R rs17782313 and FTO rs9939609 polymorphisms with susceptibility to obesity in children.
Dastgheib, Seyed Alireza; Bahrami, Reza; Setayesh, Sepideh; Salari, Seyedali; Mirjalili, Seyed Reza; Noorishadkam, Mahmood; Sadeghizadeh-Yazdi, Jalal; Akbarian, Elahe; Neamatzadeh, Hossein.
Afiliação
  • Dastgheib SA; Department of Medical Genetics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Bahrami R; Neonatal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: bahramir@sums.ac.ir.
  • Setayesh S; School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Salari S; Department of Biology, Science and Arts University, Yazd, Iran.
  • Mirjalili SR; Mother and Newborn Health Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
  • Noorishadkam M; Mother and Newborn Health Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
  • Sadeghizadeh-Yazdi J; Department of Food Science and Technology, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
  • Akbarian E; Children Growth Disorder Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
  • Neamatzadeh H; Mother and Newborn Health Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran; Department of Medical Genetics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Diabetes Metab Syndr ; 15(5): 102234, 2021.
Article em En | MEDLINE | ID: mdl-34364300
BACKGROUND AND AIM: The aim of this study was to evaluate the association of MC4R rs17782313 and FTO rs9939609 polymorphisms with childhood obesity. METHODS: A universal search was performed up to May 2021. RESULTS: A total of 31 studies including 13 studies with 9565 cases and 11956 controls on MC4R rs17782313 and 18 studies with 4789 cases and 15918 controls on FTO rs9939609 were selected. CONCLUSIONS: Pooled data showed that FTO rs9930506 and MC4R rs17782313 polymorphisms were significantly associated with obesity in children. Stratified analyses revealed that these genetic variants were associated with childhood obesity in Caucasian and Asian children.
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Predisposição Genética para Doença / Polimorfismo de Nucleotídeo Único / Receptor Tipo 4 de Melanocortina / Obesidade Infantil / Dioxigenase FTO Dependente de alfa-Cetoglutarato Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Child / Humans Idioma: En Revista: Diabetes Metab Syndr Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Irã
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Predisposição Genética para Doença / Polimorfismo de Nucleotídeo Único / Receptor Tipo 4 de Melanocortina / Obesidade Infantil / Dioxigenase FTO Dependente de alfa-Cetoglutarato Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Child / Humans Idioma: En Revista: Diabetes Metab Syndr Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Irã