Knockdown circ_0040414 inhibits inflammation, apoptosis and promotes the proliferation of cardiomyocytes via miR-186-5p/PTEN/AKT axis in chronic heart failure.

Feng, Yanling; Yan, Biao; Cheng, Hongji; Wu, Jinlei; Chen, Qinxiu; Duan, Yuexing; Zhang, Peng; Zheng, Dong; Lin, Guixiong; Zhuo, Yufeng

Feng, Yanling; Yan, Biao; Cheng, Hongji; Wu, Jinlei; Chen, Qinxiu; Duan, Yuexing; Zhang, Peng; Zheng, Dong; Lin, Guixiong; Zhuo, Yufeng.

Afiliação

Feng Y; Department of Cardiology, Panyu District He Xian Memorial Hospital, Guangzhou, Guangdong, China.
Yan B; Department of Cardiovascular, Ningbo Yinzhou No.2 Hospital, Ningbo, Zhejiang, China.
Cheng H; Department of Cardiology, Panyu District He Xian Memorial Hospital, Guangzhou, Guangdong, China.
Wu J; Department of Cardiology, Panyu District He Xian Memorial Hospital, Guangzhou, Guangdong, China.
Chen Q; Department of Cardiology, Panyu District He Xian Memorial Hospital, Guangzhou, Guangdong, China.
Duan Y; Department of Cardiology, Panyu District He Xian Memorial Hospital, Guangzhou, Guangdong, China.
Zhang P; Department of Cardiology, Panyu District He Xian Memorial Hospital, Guangzhou, Guangdong, China.
Zheng D; Department of Cardiology, Panyu District He Xian Memorial Hospital, Guangzhou, Guangdong, China.
Lin G; Department of Cardiology, Panyu District He Xian Memorial Hospital, Guangzhou, Guangdong, China.
Zhuo Y; Department of Cardiology, Panyu District He Xian Memorial Hospital, Guangzhou, Guangdong, China.

Cell Biol Int ; 45(11): 2304-2315, 2021 Nov.

Article em En | MEDLINE | ID: mdl-34369049

Assuntos

Insuficiência Cardíaca/genética; RNA Circular/genética; Adulto; Idoso; Apoptose/genética; Linhagem Celular Tumoral; Proliferação de Células/genética; Doença Crônica; Feminino; Insuficiência Cardíaca/fisiopatologia; Humanos; Inflamação/genética; Masculino; MicroRNAs/genética; MicroRNAs/metabolismo; Pessoa de Meia-Idade; Miócitos Cardíacos/metabolismo; PTEN Fosfo-Hidrolase/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; RNA Circular/metabolismo; Transdução de Sinais

Palavras-chave

Circ_0040414; apoptosis; cardiomyocytes; inflammatory; proliferation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Circular / Insuficiência Cardíaca Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Cell Biol Int Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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